Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …

Interest in biochemistry of organoselenium compound has increased in the last decades,
mainly due to their chemical and biological activities. Here, we investigated the protective …

In this review, we summarized the potential role of synthetic organoseleno compounds as
therapeutic or toxic agents, giving emphasis almost exclusively to diphenyl diselenide, the …

Oxidative stress has been pointed out as an important molecular mechanism in
methylmercury (MeHg) intoxication. At low doses, diphenyl diselenide ((PhSe) 2), a …

In 1973, two major discoveries changed the face of selenium chemistry: the identification of
the first mammal selenoenzyme, glutathione peroxidase 1, and the discovery of the synthetic …

Organodiselenides are an important class of compounds characterized by the presence of
two adjacent covalently bonded selenium nuclei. Among them, diaryldiselenides and their …

This study investigated the possible antidepressant-like and anxiolytic-like effects of
diphenyl diselenide,(PhSe) 2 in mice. The involvement of l-arginine-nitric oxide (NO)-cyclic …

The pharmacology of synthetic organoselenium compounds indicates that they can be used
as antioxidants, enzyme inhibitors, neuroprotectors, anti-tumor and anti-infectious agents …