Genetically encoded fluorescent biosensors illuminate the spatiotemporal regulation of signaling networks

EC Greenwald, S Mehta, J Zhang - Chemical reviews, 2018 - ACS Publications
Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Fluorescence lifetime measurements and biological imaging

MY Berezin, S Achilefu - Chemical reviews, 2010 - ACS Publications
When a molecule absorbs a photon of appropriate energy, a chain of photophysical events
ensues, such as internal conversion or vibrational relaxation (loss of energy in the absence …

[LIVRE][B] FRET-Förster resonance energy transfer: from theory to applications

IL Medintz, N Hildebrandt - 2013 - books.google.com
FRET–Förster Resonance Energy Transfer Meeting the need for an up-to-date and detailed
primer on all aspects of the topic, this ready reference reflects the incredible expansion in …

An improved cerulean fluorescent protein with enhanced brightness and reduced reversible photoswitching

ML Markwardt, GJ Kremers, CA Kraft, K Ray… - PloS one, 2011 - journals.plos.org
Cyan fluorescent proteins (CFPs), such as Cerulean, are widely used as donor fluorophores
in Förster resonance energy transfer (FRET) experiments. Nonetheless, the most widely …

Fluorescence resonance energy transfer microscopy as demonstrated by measuring the activation of the serine/threonine kinase Akt

JA Broussard, B Rappaz, DJ Webb, CM Brown - Nature protocols, 2013 - nature.com
This protocol describes procedures for performing fluorescence resonance energy transfer
(FRET) microscopy analysis by three different methods: acceptor photobleaching, sensitized …

Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins

H Wang, L Hu, K Dalen, H Dorward… - Journal of Biological …, 2009 - ASBMB
Lipolysis is an important metabolic pathway controlling energy homeostasis through
degradation of triglycerides stored in lipid droplets and release of fatty acids. Lipid droplets …

Fluorescence lifetime and polarization-resolved imaging in cell biology

JA Levitt, DR Matthews, SM Ameer-Beg… - Current opinion in …, 2009 - Elsevier
Fluorescence lifetime imaging (FLIM) and fluorescence polarization imaging are
complementary techniques that can be used to extract information about macromolecules …

eIF4F is a thermo-sensing regulatory node in the translational heat shock response

CD Altamirano, MK Kang, MA Jordan, T Borianne… - Molecular Cell, 2024 - cell.com
Heat-shocked cells prioritize the translation of heat shock (HS) mRNAs, but the underlying
mechanism is unclear. We report that HS in budding yeast induces the disassembly of the …

FRET microscopy in 2010: the legacy of Theodor Förster on the 100th anniversary of his birth

Y Sun, H Wallrabe, SA Seo, A Periasamy - Chemphyschem, 2011 - Wiley Online Library
The impact of great scientific insights can very often only be measured decades later.
Theodor Fçrster's theory of Fçrster (or fluorescence) resonance energy transfer (FRET) is …

A rationally enhanced red fluorescent protein expands the utility of FRET biosensors

GCH Mo, C Posner, EA Rodriguez, T Sun… - Nature …, 2020 - nature.com
Genetically encoded Förster Resonance Energy Transfer (FRET)-based biosensors are
powerful tools to illuminate spatiotemporal regulation of cell signaling in living cells, but the …