Ecology and exploration of the rare biosphere
The profound influence of microorganisms on human life and global biogeochemical cycles
underlines the value of studying the biogeography of microorganisms, exploring microbial …
underlines the value of studying the biogeography of microorganisms, exploring microbial …
Marine microbial community dynamics and their ecological interpretation
Recent advances in studying the dynamics of marine microbial communities have shown
that the composition of these communities follows predictable patterns and involves complex …
that the composition of these communities follows predictable patterns and involves complex …
Enhancing diversity analysis by repeatedly rarefying next generation sequencing data describing microbial communities
Amplicon sequencing has revolutionized our ability to study DNA collected from
environmental samples by providing a rapid and sensitive technique for microbial …
environmental samples by providing a rapid and sensitive technique for microbial …
Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice
The gut microbiota has been implicated in chronic pain disorders, including irritable bowel
syndrome (IBS), yet specific pathophysiological mechanisms remain unclear. We showed …
syndrome (IBS), yet specific pathophysiological mechanisms remain unclear. We showed …
[HTML][HTML] Age-associated microbial dysbiosis promotes intestinal permeability, systemic inflammation, and macrophage dysfunction
Levels of inflammatory mediators in circulation are known to increase with age, but the
underlying cause of this age-associated inflammation is debated. We find that, when …
underlying cause of this age-associated inflammation is debated. We find that, when …
Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome
Background & Aims Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but
little is known about their effects on psychiatric comorbidities. We performed a prospective …
little is known about their effects on psychiatric comorbidities. We performed a prospective …
Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis
Aside from centrally induced trained immunity in the bone marrow (BM) and peripheral
blood by parenteral vaccination or infection, evidence indicates that mucosal-resident innate …
blood by parenteral vaccination or infection, evidence indicates that mucosal-resident innate …
Systematic improvement of amplicon marker gene methods for increased accuracy in microbiome studies
Amplicon-based marker gene surveys form the basis of most microbiome and other
microbial community studies. Such PCR-based methods have multiple steps, each of which …
microbial community studies. Such PCR-based methods have multiple steps, each of which …
Fecal microbiota transplantation induces remission in patients with active ulcerative colitis in a randomized controlled trial
Background & Aims Ulcerative colitis (UC) is difficult to treat, and standard therapy does not
always induce remission. Fecal microbiota transplantation (FMT) is an alternative approach …
always induce remission. Fecal microbiota transplantation (FMT) is an alternative approach …
Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice
Irritable bowel syndrome (IBS) is a common disorder characterized by altered gut function
and often is accompanied by comorbid anxiety. Although changes in the gut microbiota have …
and often is accompanied by comorbid anxiety. Although changes in the gut microbiota have …