Role of nitrate reductase in NO production in photosynthetic eukaryotes

M Tejada-Jimenez, A Llamas, A Galván, E Fernández - Plants, 2019 - mdpi.com
Nitric oxide is a gaseous secondary messenger that is critical for proper cell signaling and
plant survival when exposed to stress. Nitric oxide (NO) synthesis in plants, under standard …

[HTML][HTML] The mitochondrial amidoxime reducing component—from prodrug-activation mechanism to drug-metabolizing enzyme and onward to drug target

MA Struwe, AJ Scheidig, B Clement - Journal of Biological Chemistry, 2023 - Elsevier
The mitochondrial amidoxime–reducing component (mARC) is one of five known
molybdenum enzymes in eukaryotes. mARC belongs to the MOSC domain superfamily, a …

Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes

C Kubitza, F Bittner, C Ginsel, A Havemeyer… - Proceedings of the …, 2018 - pnas.org
Biotransformation enzymes ensure a viable homeostasis by regulating reversible cycles of
oxidative and reductive reactions. The metabolism of nitrogen-containing compounds is of …

Chlamydomonas reinhardtii—A Reference Microorganism for Eukaryotic Molybdenum Metabolism

M Tejada-Jimenez, E Leon-Miranda, A Llamas - Microorganisms, 2023 - mdpi.com
Molybdenum (Mo) is vital for the activity of a small but essential group of enzymes called
molybdoenzymes. So far, specifically five molybdoenzymes have been discovered in …

Characterization of the amidoxime reducing components ARC1 and ARC2 from Arabidopsis thaliana

L Maiber, A Koprivova, D Bender, S Kopriva… - The FEBS …, 2022 - Wiley Online Library
Five molybdenum‐dependent enzymes are known in eukaryotes. While four of them are
under investigation since decades, the most recently discovered,(mitochondrial) amidoxime …

[HTML][HTML] From the eukaryotic molybdenum cofactor biosynthesis to the moonlighting enzyme mARC

M Tejada-Jimenez, A Chamizo-Ampudia, V Calatrava… - Molecules, 2018 - mdpi.com
All eukaryotic molybdenum (Mo) enzymes contain in their active site a Mo Cofactor (Moco),
which is formed by a tricyclic pyranopterin with a dithiolene chelating the Mo atom. Here, the …

[HTML][HTML] Catalytic electrochemistry of the bacterial Molybdoenzyme YcbX

P Kalimuthu, JR Harmer, M Baldauf, AH Hassan… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Molybdenum-dependent enzymes that can reduce N-hydroxylated substrates (eg N-
hydroxyl-purines, amidoximes) are found in bacteria, plants and vertebrates. They are …

[PDF][PDF] Chlamydomonas reinhardtii a Reference Microorganism for Eukaryotic Molybdenum Homeostasis

M Tejada-Jimenez, E Leon-Miranda, A Llamas - 2023 - preprints.org
Molybdenum (Mo) is vital for the activity of a small but essential group of enzymes called
molybdoenzymes. So far, specifically five molybdoenzymes have been discovered in …

[PDF][PDF] Structural Characterization of Flavin-dependent Monooxygenases from Zonocerus variegatus and the Human Mitochondrial Amidoxime Reducing Component …

C Kubitza - 2018 - macau.uni-kiel.de
Organisms are permanently exposed to foreign and harmful substances. These xenobiotics
have to undergo metabolic processes in order to be eliminated from the organism. This …