Fluorescent probes for targeting the Golgi apparatus: design strategies and applications

S Xu, KC Yan, ZH Xu, Y Wang, TD James - Chemical Society Reviews, 2024 - pubs.rsc.org
The Golgi apparatus is an essential organelle constructed by the stacking of flattened
vesicles, that is widely distributed in eukaryotic cells and is dynamically regulated during cell …

Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D

AV Krishnan, D Feldman - Annual review of pharmacology and …, 2011 - annualreviews.org
Calcitriol, the hormonally active form of vitamin D, is being evaluated in clinical trials as an
anti-cancer agent. Calcitriol exerts multiple anti-proliferative, pro-apoptotic, and pro …

Natural products for the management and prevention of breast cancer

S Mitra, R Dash - Evidence‐Based Complementary and …, 2018 - Wiley Online Library
Among all types of cancer, breast cancer is one of the most challenging diseases, which is
responsible for a large number of cancer related deaths. Hormonal therapy, surgery …

Fluorescent probes for biomolecule detection under environmental stress

X Han, Y Wang, Y Huang, X Wang, J Choo… - Journal of Hazardous …, 2022 - Elsevier
The use of fluorescent probes in visible detection has been developed over the last several
decades. Biomolecules are essential in the biological processes of organisms, and their …

Nile red and nile blue: applications and syntheses of structural analogues

V Martinez, M Henary - Chemistry–A European Journal, 2016 - Wiley Online Library
Nile red and Nile blue are highly fluorescent and photostable organic dyes from the benzo
[a] phenoxazine family. They have been used as histological stains for imaging lysosomes …

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2

TR Lyons, J O'brien, VF Borges, MW Conklin… - Nature medicine, 2011 - nature.com
The prognosis of breast cancer in young women is influenced by reproductive history.
Women diagnosed within 5 years postpartum have worse prognosis than nulliparous …

An off–on Cox-2-specific fluorescent probe: Targeting the golgi apparatus of cancer cells

H Zhang, J Fan, J Wang, S Zhang, B Dou… - Journal of the …, 2013 - ACS Publications
Identifying cancer cells and quantifying cancer-related events in particular organelles in a
rapid and sensitive fashion are important for early diagnosis and for studies on pathology …

Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer

LR Howe - Breast cancer research, 2007 - Springer
Many human cancers exhibit elevated prostaglandin (PG) levels due to upregulation of
cyclooxygenase-2 (COX-2), a key enzyme in eicosanoid biosynthesis. COX-2 over …

[HTML][HTML] Cyclooxygenase-2 and the inflammogenesis of breast cancer

RE Harris, BC Casto, ZM Harris - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
Cohesive scientific evidence from molecular, animal, and human investigations supports the
hypothesis that constitutive overexpression of cyclooxygenase-2 (COX-2) is a ubiquitous …

The bone microenvironment in metastasis; what is special about bone?

KM Bussard, CV Gay, AM Mastro - Cancer and Metastasis Reviews, 2008 - Springer
The skeleton is a common destination for many cancer metastases including breast and
prostate cancer. There are many characteristics of bone that make it an ideal environment …