Use of human umbilical vein endothelial cells (HUVEC) as a model to study cardiovascular disease: A review
DJ Medina-Leyte, M Domínguez-Pérez, I Mercado… - Applied Sciences, 2020 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death worldwide, and extensive
research has been performed to understand this disease better, using various experimental …
research has been performed to understand this disease better, using various experimental …
Autophagy at the interface of endothelial cell homeostasis and vascular disease
E Mameli, A Martello, A Caporali - The FEBS journal, 2022 - Wiley Online Library
Autophagy is an essential intracellular process for cellular quality control. It enables cell
homeostasis through the selective degradation of harmful protein aggregates and damaged …
homeostasis through the selective degradation of harmful protein aggregates and damaged …
The role of autophagy in cardiovascular pathology
Macroautophagy/autophagy is a conserved catabolic recycling pathway in which
cytoplasmic components are sequestered, degraded, and recycled to survive various stress …
cytoplasmic components are sequestered, degraded, and recycled to survive various stress …
Targeting tumor innervation: premises, promises, and challenges
X Li, X Peng, S Yang, S Wei, Q Fan, J Liu, L Yang… - Cell death …, 2022 - nature.com
A high intratumoral nerve density is correlated with poor survival, high metastasis, and high
recurrence across multiple solid tumor types. Recent research has revealed that cancer cells …
recurrence across multiple solid tumor types. Recent research has revealed that cancer cells …
Phosphoregulation of the autophagy machinery by kinases and phosphatases
Eukaryotic cells use post-translational modifications to diversify and dynamically coordinate
the function and properties of protein networks within various cellular processes. For …
the function and properties of protein networks within various cellular processes. For …
Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapse
M Overhoff, F Tellkamp, S Hess, M Tolve, J Tutas… - The EMBO …, 2022 - embopress.org
Autophagy provides nutrients during starvation and eliminates detrimental cellular
components. However, accumulating evidence indicates that autophagy is not merely a …
components. However, accumulating evidence indicates that autophagy is not merely a …
The multifaceted functions of ATG16L1 in autophagy and related processes
N Gammoh - Journal of cell science, 2020 - journals.biologists.com
Autophagy requires the formation of membrane vesicles, known as autophagosomes, that
engulf cellular cargoes and subsequently recruit lysosomal hydrolases for the degradation …
engulf cellular cargoes and subsequently recruit lysosomal hydrolases for the degradation …
Selective autophagy of AKAP11 activates cAMP/PKA to fuel mitochondrial metabolism and tumor cell growth
Z Deng, X Li, M Blanca Ramirez… - Proceedings of the …, 2021 - National Acad Sciences
Autophagy is a catabolic pathway that provides self-nourishment and maintenance of
cellular homeostasis. Autophagy is a fundamental cell protection pathway through metabolic …
cellular homeostasis. Autophagy is a fundamental cell protection pathway through metabolic …
PKA compartmentalization links cAMP signaling and autophagy
F Grisan, LF Iannucci, NC Surdo, A Gerbino… - Cell Death & …, 2021 - nature.com
Autophagy is a highly regulated degradative process crucial for maintaining cell
homeostasis. This important catabolic mechanism can be nonspecific, but usually occurs …
homeostasis. This important catabolic mechanism can be nonspecific, but usually occurs …
ZDHHC7-mediated S-palmitoylation of ATG16L1 facilitates LC3 lipidation and autophagosome formation
F Wei, Y Wang, J Yao, L Mei, X Huang, H Kong… - Autophagy, 2024 - Taylor & Francis
Macroautophagy/autophagy is a fundamental cellular catabolic process that delivers
cytoplasmic components into double-membrane vesicles called autophagosomes, which …
cytoplasmic components into double-membrane vesicles called autophagosomes, which …