Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …

The pathophysiology of major depressive disorder (MDD) is thought to result from impaired
connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key …

One of the most important characteristics of the brain compared to other organs is its
elevated metabolic demand. Consequently, neurons consume high quantities of oxygen …

Abstract γ-Aminobutyric acid (GABA), an important inhibitory neurotransmitter in the central
nervous system, is recycled through specific GABA transporters (GATs). GAT1, which is …

Alzheimer's disease (AD) is the most frequent cause of cognitive impairment in middle-aged
and older populations. There is a lack of drugs that demonstrate significant efficacy in AD, so …

The greater prevalence and incidence of Parkinson's disease (PD) in men suggest a
beneficial effect of sex hormones. Neuroactive steroids have neuroprotective activities thus …

GABA is the most common inhibitory neurotransmitter in the vertebrate central nervous
system. Synthesized by glutamic acid decarboxylase, GABA could specifically bind with two …

In the era of plastic use, organisms are constantly exposed to polystyrene particles (PS-Ps).
PS-Ps accumulated in living organisms exert negative effects on the body, although studies …

Sedatives promote calmness or sleepiness during surgery or severely stressful events. In
addition, depression is a mental health issue that negatively affects emotional well-being. A …

Neurotransmitters are considered as a fundamental regulator in the process of neuronal
growth, differentiation and survival. Parkinson's Disease (PD) occurs due to extensive …