Chitosan: An overview of biological activities, derivatives, properties, and current advancements in biomedical applications.
The second and most often utilized natural polymer is chitosan (CS), a naturally existing
amino polysaccharide that is produced by deacetylating chitin. Numerous applications have …
amino polysaccharide that is produced by deacetylating chitin. Numerous applications have …
Advances in infectious disease vaccine adjuvants
Vaccines are one of the most significant medical interventions in the fight against infectious
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …
Vaccines, adjuvants and key factors for mucosal immune response
Vaccines are the most effective tool to control infectious diseases, which provoke significant
morbidity and mortality rates. Most vaccines are administered through the parenteral route …
morbidity and mortality rates. Most vaccines are administered through the parenteral route …
CTNNB1 alternation is a potential biomarker for immunotherapy prognosis in patients with hepatocellular carcinoma
L Chen, Q Zhou, J Liu, W Zhang - Frontiers in Immunology, 2021 - frontiersin.org
Background The emergence of immune checkpoint inhibitors (ICIs) marks the beginning of a
new era of immunotherapy for hepatocellular carcinoma (HCC), however, not all patients …
new era of immunotherapy for hepatocellular carcinoma (HCC), however, not all patients …
Combinatorial herpes simplex vaccine strategies: from bedside to bench and back
AA Chentoufi, NR Dhanushkodi, R Srivastava… - Frontiers in …, 2022 - frontiersin.org
The development of vaccines against herpes simplex virus type 1 and type 2 (HSV1 and
HSV-2) is an important goal for global health. In this review we reexamined (i) the status of …
HSV-2) is an important goal for global health. In this review we reexamined (i) the status of …
Immunotherapy in melanoma: advances, pitfalls, and future perspectives
C Sorino, S Iezzi, L Ciuffreda, I Falcone - Frontiers in Molecular …, 2024 - frontiersin.org
Cutaneous melanoma is the deadliest and most aggressive form of skin cancer owing to its
high capacity for metastasis. Over the past few decades, the management of this type of …
high capacity for metastasis. Over the past few decades, the management of this type of …
The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination
Abstract Development of effective human immunodeficiency virus 1 (HIV-1) vaccines
requires synergy between innate and adaptive immune cells. Here we show that induction of …
requires synergy between innate and adaptive immune cells. Here we show that induction of …
Promising adjuvants and platforms for influenza vaccine development
Influenza is one of the major threats to public health. Current influenza vaccines cannot
provide effective protection against drifted or shifted influenza strains. Researchers have …
provide effective protection against drifted or shifted influenza strains. Researchers have …
Discovery of new states of immunomodulation for vaccine adjuvants via high throughput screening: expanding innate responses to PRRs
Stimulation of the innate immune system is crucial in both effective vaccinations and
immunotherapies. This is often achieved through adjuvants, molecules that usually activate …
immunotherapies. This is often achieved through adjuvants, molecules that usually activate …
mRNA Vaccine Nanoplatforms and Innate Immunity
mRNA-based vaccine technology has been significantly developed and enhanced,
particularly highlighted by the authorization of mRNA vaccines for addressing the COVID-19 …
particularly highlighted by the authorization of mRNA vaccines for addressing the COVID-19 …