Dibenzazepine-linked isoxazoles: New and potent class of α-glucosidase inhibitors
Abstract α-Glucosidase inhibition is a valid approach for controlling hyperglycemia in
diabetes. In the current study, new molecules as a hybrid of isoxazole and dibenzazepine …
diabetes. In the current study, new molecules as a hybrid of isoxazole and dibenzazepine …
Synthesis of N-substituted dibenzoazepine–pyridazine derivatives as potential neurologically active drugs
Syntheses of pyridazine derivatives of dibenzoazepine, starting from N-substituted-
dibenzoazepines, are reported here for the first time. In the reaction sequence, N-substitute …
dibenzoazepines, are reported here for the first time. In the reaction sequence, N-substitute …
Synthesis and in vitro evaluation of dibenzoazepine triazole derivatives: A novel class of antileishmanial agents
M Aqeel Khan, A Saleem, N Ghouri… - Letters in Drug …, 2015 - benthamdirect.com
In the present study, a series of dibenzoazepine triazole derivatives (24-39) were
synthesized and evaluated for their in vitro bioactivities including antiglycation, antibacterial …
synthesized and evaluated for their in vitro bioactivities including antiglycation, antibacterial …
Synthesis, molecular docking and in vivo biological evaluation of Iminostilbene linked 1, 2, 3-triazole pharmacophores as promising anti-anxiety and anti-inflammatory …
Background: Iminostilbene and 1, 2, 3-triazole ring containing compounds are considered
as beneficial substrates in drug design. Objectives: This study was aimed at the synthesis of …
as beneficial substrates in drug design. Objectives: This study was aimed at the synthesis of …
Five closely related 4-chloro-6, 11-dihydro-5H-benzo [b] pyrimido [5, 4-f] azepines: similar molecular structures but different supramolecular assemblies
LM Acosta, J Jurado, A Palma, J Cobo… - … Section C: Structural …, 2015 - journals.iucr.org
Dibenz [b, f] azepine (DBA) is a privileged 6-7-6 tricyclic ring system of importance in both
organic and medicinal chemistry. Benzo [b] pyrimido [5, 4-f] azepines (BPAs), which also …
organic and medicinal chemistry. Benzo [b] pyrimido [5, 4-f] azepines (BPAs), which also …
[PDF][PDF] 5-(Prop-2-yn-1-yl)-5H-dibenzo [b, f] azepine: orthorhombic polymorph
In the title orthorhombic polymorph (space group Iba2), C17H13N, the dihedral angle
between the benzene rings is 55.99 (10)° and the azepine ring adopts a boat conformation …
between the benzene rings is 55.99 (10)° and the azepine ring adopts a boat conformation …
Solvent-free protocol for the green synthesis of benzamide analogs of dibenzoazepine
MA Khan, F Batool, A Khatoon, R Sadiq… - European Journal of …, 2017 - eurjchem.com
Dibenzoazepine represents an important class of heterocycles, exhibiting potent
antidepressant and anticonvulsant activities. Beside, various modifications on this nucleus …
antidepressant and anticonvulsant activities. Beside, various modifications on this nucleus …