Microfluidic platforms integrated with nano-sensors for point-of-care bioanalysis
Microfluidic technology provides a portable, cost-effective, and versatile tool for point-of-care
(POC) bioanalysis because of its associated advantages such as fast analysis, low volumes …
(POC) bioanalysis because of its associated advantages such as fast analysis, low volumes …
Quantitative or digital PCR? A comparative analysis for choosing the optimal one for biosensing applications
This paper offers an exhaustive comparison of quantitative PCR (qPCR) and digital PCR
(dPCR) technologies, focusing on their critical roles in molecular diagnostics, ranging from …
(dPCR) technologies, focusing on their critical roles in molecular diagnostics, ranging from …
High-throughput microfluidic systems accelerated by artificial intelligence for biomedical applications
J Zhou, J Dong, H Hou, L Huang, J Li - Lab on a Chip, 2024 - pubs.rsc.org
High-throughput microfluidic systems are widely used in biomedical fields for tasks like
disease detection, drug testing, and material discovery. Despite the great advances in …
disease detection, drug testing, and material discovery. Despite the great advances in …
Direct single-cell antimicrobial susceptibility testing of Escherichia coli in urine using a ready-to-use 3D microwell array chip
Empirical antibiotic therapies are prescribed for treating uncomplicated urinary tract
infections (UTIs) due to the long turnaround time of conventional antimicrobial susceptibility …
infections (UTIs) due to the long turnaround time of conventional antimicrobial susceptibility …
[HTML][HTML] Harnessing CRISPR/Cas Systems for DNA and RNA Detection: Principles, Techniques, and Challenges
H Son - Biosensors, 2024 - mdpi.com
The emergence of CRISPR/Cas systems has revolutionized the field of molecular
diagnostics with their high specificity and sensitivity. This review provides a comprehensive …
diagnostics with their high specificity and sensitivity. This review provides a comprehensive …
An optofluidic platform for cell-counting applications
Cell-counting is critical for a wide range of applications, eg, life sciences, medicine, or
pharmacology. Hemocytometry is a classical method that requires manual counting of cells …
pharmacology. Hemocytometry is a classical method that requires manual counting of cells …
A one-stage deep learning based method for automatic analysis of droplet-based digital PCR images
Y Yao, S Zhao, Y Liang, F Hu, N Peng - Analyst, 2023 - pubs.rsc.org
Droplet-based dPCR offers many advantages over chip-based dPCR, such as lower
processing cost, higher droplet density, higher throughput, while requiring less sample …
processing cost, higher droplet density, higher throughput, while requiring less sample …
SAM‐dPCR: Accurate and Generalist Nuclei Acid Quantification Leveraging the Zero‐Shot Segment Anything Model
Digital PCR (dPCR) has transformed nucleic acid diagnostics by enabling the absolute
quantification of rare mutations and target sequences. However, traditional dPCR detection …
quantification of rare mutations and target sequences. However, traditional dPCR detection …
Deep‐qGFP: A Generalist Deep Learning Assisted Pipeline for Accurate Quantification of Green Fluorescent Protein Labeled Biological Samples in Microreactors
Absolute quantification of biological samples provides precise numerical expression levels,
enhancing accuracy, and performance for rare templates. Current methodologies, however …
enhancing accuracy, and performance for rare templates. Current methodologies, however …
Engineering innovative interfaces for point-of-care diagnostics
The ongoing Coronavirus disease 2019 (COVID-19) pandemic illustrates the need for
sensitive and reliable tools to diagnose and monitor diseases. Traditional diagnostic …
sensitive and reliable tools to diagnose and monitor diseases. Traditional diagnostic …