Alzheimer's disease pathology is closely connected to the processing of the amyloid
precursor protein (APP) resulting in the formation of a variety of amyloid-beta (Aβ) peptides …

The final goal of functional genomics is to determine the biological role for all of the genes in
a cell. At present, the genome-scale prediction of protein function is based primarily on the …

Recently, we documented that the short, proline-rich antibacterial peptides pyrrhocoricin,
drosocin, and apidaecin interact with the bacterial heat shock protein DnaK, and peptide …

Electron paramagnetic resonance spectroscopy analysis of 19 spin-labeled derivatives of
the Alzheimer's amyloid β (Aβ) peptide was used to reveal structural features of amyloid fibril …

The amyloid cascade hypothesis of Alzheimer's disease (AD) proposes amyloid-β (Aβ) is a
chief pathological element of dementia. AD therapies have targeted monomeric and …

Alzheimer's disease (AD) paired helical filaments (PHFs), building blocks of neurofibrillary
tangles (NFTs) are composed of hyperphosphorylated forms of the microtubule-associated …

The deamidation reactions of asparagine residues in α‐helical and β‐turn secondary
structural environments of peptides and proteins are reviewed. Both kinds of secondary …

Members of the proline‐rich antibacterial peptide family, pyrrhocoricin, apidaecin and
drosocin appear to kill responsive bacterial species by binding to the multihelical lid region …

Phosphorylated osteopontin peptides suppress crystallization by inhibiting the growth of
calcium oxalate crystals. Background Osteopontin isolated from human urine [uropontin …

Recent advances have placed the pro-inflammatory activity of amyloid β (Aβ) on microglia
cells as the focus of research on Alzheimer's Disease (AD). Researchers are confronted with …