Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

Many studies of the human brain have explored the relationship between cortical thickness
and cognition, phenotype, or disease. Due to the subjectivity and time requirements in …

Cross-sectional comparisons have consistently revealed that increased age is associated
with lower levels of cognitive performance, even in the range from 18 to 60 years of age …

Cortical folding is a hallmark of many, but not all, mammalian brains. The degree of folding
increases with brain size across mammals, but at different scales between orders and …

Older adults exhibit global reductions in cortical surface area, but little is known about the
regional patterns of reductions or how these relate to other measures of brain structure. This …

Objective Longitudinal structural MRI studies have shown that patients with schizophrenia
have progressive brain tissue loss after onset. Recurrent relapses are believed to play a role …

Backgroud Major depression is a frequent psychiatric complication among patients with
traumatic brain injury (TBI). To our knowledge, however, the clinical correlates of major …

We examined age-, sex-, and hemisphere-related differences in the cerebral cortex.
Volumes of the cerebral hemispheres and 13 regions of interest (ROIs) were measured on …

BACKGROUND: Schizophrenia has a characteristic onset during adolescence or young
adulthood but also tends to persist throughout life. Structural magnetic resonance studies …