Target identification is an important step in drug discovery, and computer-aided drug target
identification methods are attracting more attention compared with traditional drug target …

Drug discovery is important in cancer therapy and precision medicines. Traditional
approaches of drug discovery are mainly based on in vivo animal experiments and in vitro …

At the initial stage of drug discovery, identifying novel targets with maximal efficacy and
minimal side effects can improve the success rate and portfolio value of drug discovery …

The escalating prevalence of hyperlipidemia has a profound impact on individuals' daily
physiological well-being. The traditional Chinese medicine (TCM) prescription Danggui …

Acupuncture is an important part of Chinese medicine that has been widely used in the
treatment of inflammatory diseases. During the coronavirus disease 2019 (COVID-19) …

Biomedical discovery has been reshaped upon the exploding digitization of data which can
be retrieved from a number of sources, ranging from clinical pharmacology to …

CNS disorders are indications with a very high unmet medical needs, relatively smaller
number of available drugs, and a subpar satisfaction level among patients and caregiver …

The volume of biological, chemical and functional data deposited in the public domain is
growing rapidly, thanks to next generation sequencing and highly-automated screening …

Background Previous studies have demonstrated that high-density lipoprotein cholesterol
(HDL-C) plays an anti-atherosclerosis role through reverse cholesterol transport. Several …

Aim: Uterine leiomyoma is the most common benign tumor of female genitalia, and the
incidence is rising gradually. This study explores the mechanism of miR-29 and STAT3 …