Asymmetric organocatalytic cyclization and cycloaddition reactions

A Moyano, R Rios - Chemical Reviews, 2011 - ACS Publications
The stereocontrolled construction of chiral carbo-and heterocycles is a topic of paramount
importance in modern organic synthesis, driven by the predominance of chiral mono-and …

Enantioselective organocatalysis

PI Dalko, L Moisan - Angewandte Chemie International Edition, 2001 - Wiley Online Library
The last few years have witnessed a spectacular advancement in new catalytic methods
based on metal‐free organic molecules. In many cases, these small compounds give rise to …

Catalytic Enantioselective Cycloaddition Transformation of Tricyclic Arenes Enabled by a Dual-Role Chiral Cage-Reactor

J Chen, X Wu, S Huang, J Yang, YL Lu, Z Jiao… - ACS …, 2024 - ACS Publications
An enzyme mimic catalytic system was established by employing a chiral metal–organic
cage as the supramolecular reactor, and asymmetric dearomative Diels–Alder (D–A) …

Catalytic asymmetric diels alder reactions

HB Kagan, O Riant - Chemical reviews, 1992 - ACS Publications
The Diels-Alder reaction is a standard method for six-membered ring formation, 1* It allows
inprinciple the formationof four contiguous asymmetric centers. Relative stereochemistry is …

Catalytic enantioselective [4+ 2]-cycloaddition: a strategy to access aza-hexacycles

G Masson, C Lalli, M Benohoud… - Chemical Society …, 2013 - pubs.rsc.org
The aza-Diels Alder reaction has become one of the most widely used synthetic tools for the
preparation of N-containing 6-membered heterocycles. Numerous important developments …

Amino acids and peptides as asymmetric organocatalysts

ER Jarvo, SJ Miller - Tetrahedron, 2002 - Elsevier
Many enzymes are remarkable asymmetric catalysts, performing reactions effectively and
selectively. Aspiring to imitate enzymatic efficiencies, chemists have delved into Nature's …

Cinchona alkaloids in asymmetric organocatalysis

T Marcelli, H Hiemstra - Synthesis, 2010 - thieme-connect.com
This article reviews the applications of cinchona alkaloids as asymmetric catalysts. In the last
few years, characterized by the resurgence of interest in asymmetric organocatalysis …

Recent applications of Cinchona alkaloids and their derivatives as catalysts in metal-free asymmetric synthesis

EMO Yeboah, SO Yeboah, GS Singh - Tetrahedron, 2011 - Elsevier
The Cinchona alkaloids are natural products found in the bark of trees of the genus
Cinchona. The genus comprises about 40 species of trees or shrubs in the family Rubiaceae …

The isoinversion principle—A general model of chemical selectivity

H Buschmann, HD Scharf… - … International Edition in …, 1991 - Wiley Online Library
A large number of successful methods for chirality transfer, using either stoichiometric or
catalytic chiral auxiliaries, are in use today. However, there is a lack of practical and dynamic …

Cinchona alkaloids and their derivatives: versatile catalysts and ligands in asymmetric synthesis

K Kacprzak, J Gawroński - Synthesis, 2001 - thieme-connect.com
Cinchona alkaloids and their derivatives can catalyze an amazing array of synthetically
important reactions, providing access to chiral products of high enantiopurity. A review of …