Evolution of systemic therapy for stages I–III non-metastatic non-small-cell lung cancer

JE Chaft, A Rimner, W Weder, CG Azzoli… - Nature reviews Clinical …, 2021 - nature.com
The treatment goal for patients with early-stage lung cancer is cure. Multidisciplinary
discussions of surgical resectability and medical operability determine the modality of …

Contemporary radiotherapy: present and future

RA Chandra, FK Keane, FEM Voncken, CR Thomas - The Lancet, 2021 - thelancet.com
Oncology care is increasingly a multidisciplinary endeavour, and radiation therapy
continues to have a key role across the disease spectrum in nearly every cancer. However …

Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified …

JY Chang, RJ Mehran, L Feng, V Verma, Z Liao… - The Lancet …, 2021 - thelancet.com
Background A previous pooled analysis of the STARS and ROSEL trials showed higher
survival after stereotactic ablative radiotherapy (SABR) than with surgery for operable early …

Stereotactic ablative radiotherapy with or without immunotherapy for early-stage or isolated lung parenchymal recurrent node-negative non-small-cell lung cancer: an …

JY Chang, SH Lin, W Dong, Z Liao, SJ Gandhi, CM Gay… - The Lancet, 2023 - thelancet.com
Background Stereotactic ablative radiotherapy (SABR) is the standard treatment for
medically inoperable early-stage non-small-cell lung cancer (NSCLC), but regional or …

Integrated MRI-guided radiotherapy—opportunities and challenges

PJ Keall, C Brighi, C Glide-Hurst, G Liney… - Nature Reviews …, 2022 - nature.com
MRI can help to categorize tissues as malignant or non-malignant both anatomically and
functionally, with a high level of spatial and temporal resolution. This non-invasive imaging …

Radiotherapy treatment for lung cancer: Current status and future directions

SK Vinod, E Hau - Respirology, 2020 - Wiley Online Library
Radiotherapy is an important modality used for the treatment of lung cancer. Seventy‐seven
percent of all patients with lung cancer have an evidence‐based indication for radiotherapy …

KEAP1/NFE2L2 Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

MS Binkley, YJ Jeon, M Nesselbush, EJ Moding… - Cancer discovery, 2020 - AACR
Tumor genoty** is not routinely performed in localized non–small cell lung cancer
(NSCLC) due to lack of associations of mutations with outcome. Here, we analyze 232 …

Radiotherapy and theranostics: A lancet oncology commission

M Abdel-Wahab, F Giammarile, M Carrara… - The lancet …, 2024 - thelancet.com
Following on from the 2015 Lancet Oncology Commission on expanding global access to
radiotherapy, Radiotherapy and theranostics: a Lancet Oncology Commission was created …

The evolving role of radiotherapy in non-small cell lung cancer

S Brown, K Banfill, MC Aznar… - The British journal of …, 2019 - academic.oup.com
Lung cancer is the most commonly diagnosed cancer and biggest cause of cancer mortality
worldwide with non-small cell lung cancer (NSCLC) accounting for most cases …

Rational combinations of immunotherapy with radiotherapy in ovarian cancer

FG Herrera, M Irving, LE Kandalaft, G Coukos - The Lancet Oncology, 2019 - thelancet.com
Except for its use in palliative care, radiotherapy has been largely abandoned in the
management of ovarian cancer because of the recognised efficacy and lower toxicity of …