The term 'mechanosensation'describes the capacity of cells to translate mechanical stimuli
into the coordinated regulation of intracellular signals, cellular function, gene expression …

Type 2 diabetes is a redox disease. Oxidative stress and chronic inflammation induce a
switch of metabolic homeostatic set points, leading to glucose intolerance. Several diabetes …

Abstract Purpose of Review With the intention to summarize the currently available evidence
on the pathophysiological relevance of inflammation in heart failure, this review addresses …

Pyroptotic cell death or pyroptosis is characterized by caspase-1-dependent formation of
plasma membrane pores, leading to the release of pro-inflammatory cytokines and cell lysis …

Background Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)
inflammasome is associated with metabolic disorder and cell death, which are important …

Objectives: In this study, we have investigated the effects of cannabidiol (CBD) on
myocardial dysfunction, inflammation, oxidative/nitrative stress, cell death, and interrelated …

Background Diabetes mellitus (DM) is a major public health problem which prevalence is
constantly raising, particularly in low-and middle-income countries. Both diabetes mellitus …

Metabolic disorders such as obesity, insulin resistance and type 2 diabetes mellitus are all
linked to cardiovascular diseases such as cardiac hypertrophy and heart failure. Diabetic …

Hyperglycemia‐induced oxidative stress and fibrosis play a crucial role in the development
of diabetic cardiomyopathy (DCM). Tetrahydrocurcumin (THC), a major bioactive metabolite …

Prospective population studies in the primary prevention setting have shown that reduced
plasma levels of HDL cholesterol are associated with an increased risk of coronary disease …