An overview of calf diarrhea-infectious etiology, diagnosis, and intervention
Y Cho, KJ Yoon - Journal of veterinary science, 2014 - synapse.koreamed.org
Calf diarrhea is a commonly reported disease in young animals, and still a major cause of
productivity and economic loss to cattle producers worldwide. In the report of the 2007 …
productivity and economic loss to cattle producers worldwide. In the report of the 2007 …
Human tumor-associated macrophage and monocyte transcriptional landscapes reveal cancer-specific reprogramming, biomarkers, and therapeutic targets
The roles of tumor-associated macrophages (TAMs) and circulating monocytes in human
cancer are poorly understood. Here, we show that monocyte subpopulation distribution and …
cancer are poorly understood. Here, we show that monocyte subpopulation distribution and …
Multiplexed droplet single-cell RNA-sequencing using natural genetic variation
Droplet single-cell RNA-sequencing (dscRNA-seq) has enabled rapid, massively parallel
profiling of transcriptomes. However, assessing differential expression across multiple …
profiling of transcriptomes. However, assessing differential expression across multiple …
Sublethal cytochrome c release generates drug-tolerant persister cells
Drug-tolerant persister cells (persisters) evade apoptosis upon targeted and conventional
cancer therapies and represent a major non-genetic barrier to effective cancer treatment …
cancer therapies and represent a major non-genetic barrier to effective cancer treatment …
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism
Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated
fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid …
fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid …
A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer's disease
Alzheimer's disease (AD) remains one of the grand challenges facing human society. Much
controversy exists around the complex and multifaceted pathogenesis of this prevalent …
controversy exists around the complex and multifaceted pathogenesis of this prevalent …
Biological databases for human research
The completion of the Human Genome Project lays a foundation for systematically studying
the human genome from evolutionary history to precision medicine against diseases. With …
the human genome from evolutionary history to precision medicine against diseases. With …
HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources
A Lebeau, D Bruyere, P Roncarati, P Peixoto… - Nature …, 2022 - nature.com
Despite the high prevalence of both cervico-vaginal human papillomavirus (HPV) infection
and bacterial vaginosis (BV) worldwide, their causal relationship remains unclear. While BV …
and bacterial vaginosis (BV) worldwide, their causal relationship remains unclear. While BV …
A critical role of nuclear m6A reader YTHDC1 in leukemogenesis by regulating MCM complex–mediated DNA replication
YTHDC1 has distinct functions as a nuclear N 6-methyladenosine (m6A) reader in
regulating RNA metabolism. Here we show that YTHDC1 is overexpressed in acute myeloid …
regulating RNA metabolism. Here we show that YTHDC1 is overexpressed in acute myeloid …
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope
S Lee, JW Carrasquillo Rodrı́guez, H Merta… - Journal of Cell …, 2023 - rupress.org
Lipid composition determines organelle identity; however, whether the lipid composition of
the inner nuclear membrane (INM) domain of the ER contributes to its identity is not known …
the inner nuclear membrane (INM) domain of the ER contributes to its identity is not known …