Cholangiocarcinoma—novel biological insights and therapeutic strategies

SI Ilyas, S Affo, L Goyal, A Lamarca… - Nature Reviews …, 2023 - nature.com
In the past 5 years, important advances have been made in the scientific understanding and
clinical management of cholangiocarcinoma (CCA). The cellular immune landscape of CCA …

Pathogenesis of cholangiocarcinoma

PM Rodrigues, P Olaizola, NA Paiva… - Annual Review of …, 2021 - annualreviews.org
Cholangiocarcinoma (CCA) encompasses a group of malignancies that can arise at any
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …

EASL Clinical Practice Guidelines on sclerosing cholangitis

O Chazouilleres, U Beuers, A Bergquist, TH Karlsen… - Journal of …, 2022 - Elsevier
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

[HTML][HTML] Recurrent rearrangements in PRKACA and PRKACB in intraductal oncocytic papillary neoplasms of the pancreas and bile duct

AD Singhi, LD Wood, E Parks, MS Torbenson… - Gastroenterology, 2020 - Elsevier
Background & Aims Intraductal oncocytic papillary neoplasms (IOPNs) of the pancreas and
bile duct contain epithelial cells with numerous, large mitochondria and are cystic precursors …

ACG clinical guideline: diagnosis and management of biliary strictures

BJ Elmunzer, JL Maranki, V Gómez… - Official journal of the …, 2023 - journals.lww.com
A biliary stricture is an abnormal narrowing in the ductal drainage system of the liver that can
result in clinically and physiologically relevant obstruction to the flow of bile. The most …

[HTML][HTML] Molecular profiling in cholangiocarcinoma: a practical guide to next-generation sequencing

A Stenzinger, A Vogel, U Lehmann, A Lamarca… - Cancer Treatment …, 2024 - Elsevier
Cholangiocarcinomas (CCA) are a heterogeneous group of tumors that are classified as
intrahepatic, perihilar, or distal according to the anatomic location within the biliary tract …

The World Health Organization reporting system for pancreaticobiliary cytopathology

MB Pitman, BA Centeno, MD Reid, MT Siddiqui… - Acta Cytologica, 2023 - karger.com
Abstract The World Health Organization (WHO), the International Academy of Cytology, and
the International Agency for Research on Cancer, with expert contributors from around the …

Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures

M Arechederra, M Rullán, I Amat, D Oyon, L Zabalza… - Gut, 2022 - gut.bmj.com
Objective Despite significant progresses in imaging and pathological evaluation, early
differentiation between benign and malignant biliary strictures remains challenging …

Whole‐genome bisulfite sequencing analysis of circulating tumour DNA for the detection and molecular classification of cancer

Y Gao, H Zhao, K An, Z Liu, L Hai, R Li… - Clinical and …, 2022 - Wiley Online Library
Background Cancer cell–specific variation and circulating tumour DNA (ctDNA) methylation
are promising biomarkers for non‐invasive cancer detection and molecular classification …

British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma

SM Rushbrook, TJ Kendall, Y Zen, R Albazaz… - Gut, 2024 - gut.bmj.com
These guidelines for the diagnosis and management of cholangiocarcinoma (CCA) were
commissioned by the British Society of Gastroenterology liver section. The guideline writing …