[HTML][HTML] Role of lncRNA LUCAT1 in cancer

C **ng, S Sun, ZQ Yue, F Bai - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Long non-coding RNAs (lncRNAs) are RNA molecules with a transcript length of more than
200 nt and lack a protein-coding ability. They regulate gene expression by interacting with …

History, discovery, and classification of lncRNAs

J Jarroux, A Morillon, M Pinskaya - Long non coding RNA biology, 2017 - Springer
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …

Cytoplasmic functions of long noncoding RNAs

JH Noh, KM Kim, WG McClusky… - Wiley …, 2018 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …

Long noncoding RNAs: from clinical genetics to therapeutic targets?

RA Boon, N Jaé, L Holdt, S Dimmeler - Journal of the American College of …, 2016 - jacc.org
Recent studies suggest that the majority of the human genome is transcribed, but only about
2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a …

Long non-coding RNAs in the cytoplasm

F Rashid, A Shah, G Shan - Genomics, proteomics and …, 2016 - academic.oup.com
An enormous amount of long non-coding RNAs (lncRNAs) transcribed from eukaryotic
genome are important regulators in different aspects of cellular events. Cytoplasm is the …

Regulatory RNAs in heart failure

CPC Gomes, B Schroen, GM Kuster, EL Robinson… - Circulation, 2020 - ahajournals.org
Cardiovascular disease is an enormous socioeconomic burden worldwide and remains a
leading cause of mortality and disability despite significant efforts to improve treatments and …

H19 induces abdominal aortic aneurysm development and progression

DY Li, A Busch, H **, E Chernogubova, J Pelisek… - Circulation, 2018 - ahajournals.org
Background: Long noncoding RNAs have emerged as critical molecular regulators in
various biological processes and diseases. Here we sought to identify and functionally …

The role of lncRNAs in gene expression regulation through mRNA stabilization

M Sebastian-delaCruz, I Gonzalez-Moro… - Non-coding RNA, 2021 - mdpi.com
mRNA stability influences gene expression and translation in almost all living organisms,
and the levels of mRNA molecules in the cell are determined by a balance between …

HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP

JH Noh, KM Kim, K Abdelmohsen, JH Yoon… - Genes & …, 2016 - genesdev.cshlp.org
Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the
mechanisms that mediate their transport to mitochondria are poorly characterized. Using …

The H19 Long non-coding RNA in cancer initiation, progression and metastasis–a proposed unifying theory

E Raveh, IJ Matouk, M Gilon, A Hochberg - Molecular cancer, 2015 - Springer
The imprinted oncofetal long non-coding RNA (lncRNA) H19 is expressed in the embryo,
down-regulated at birth and then reappears in tumors. Its role in tumor initiation and …