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[HTML][HTML] Role of lncRNA LUCAT1 in cancer
C **ng, S Sun, ZQ Yue, F Bai - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Long non-coding RNAs (lncRNAs) are RNA molecules with a transcript length of more than
200 nt and lack a protein-coding ability. They regulate gene expression by interacting with …
200 nt and lack a protein-coding ability. They regulate gene expression by interacting with …
History, discovery, and classification of lncRNAs
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
Cytoplasmic functions of long noncoding RNAs
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
Long noncoding RNAs: from clinical genetics to therapeutic targets?
Recent studies suggest that the majority of the human genome is transcribed, but only about
2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a …
2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a …
Long non-coding RNAs in the cytoplasm
An enormous amount of long non-coding RNAs (lncRNAs) transcribed from eukaryotic
genome are important regulators in different aspects of cellular events. Cytoplasm is the …
genome are important regulators in different aspects of cellular events. Cytoplasm is the …
Regulatory RNAs in heart failure
Cardiovascular disease is an enormous socioeconomic burden worldwide and remains a
leading cause of mortality and disability despite significant efforts to improve treatments and …
leading cause of mortality and disability despite significant efforts to improve treatments and …
H19 induces abdominal aortic aneurysm development and progression
Background: Long noncoding RNAs have emerged as critical molecular regulators in
various biological processes and diseases. Here we sought to identify and functionally …
various biological processes and diseases. Here we sought to identify and functionally …
The role of lncRNAs in gene expression regulation through mRNA stabilization
M Sebastian-delaCruz, I Gonzalez-Moro… - Non-coding RNA, 2021 - mdpi.com
mRNA stability influences gene expression and translation in almost all living organisms,
and the levels of mRNA molecules in the cell are determined by a balance between …
and the levels of mRNA molecules in the cell are determined by a balance between …
HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP
Some mitochondrial long noncoding RNAs (lncRNAs) are encoded by nuclear DNA, but the
mechanisms that mediate their transport to mitochondria are poorly characterized. Using …
mechanisms that mediate their transport to mitochondria are poorly characterized. Using …
The H19 Long non-coding RNA in cancer initiation, progression and metastasis–a proposed unifying theory
E Raveh, IJ Matouk, M Gilon, A Hochberg - Molecular cancer, 2015 - Springer
The imprinted oncofetal long non-coding RNA (lncRNA) H19 is expressed in the embryo,
down-regulated at birth and then reappears in tumors. Its role in tumor initiation and …
down-regulated at birth and then reappears in tumors. Its role in tumor initiation and …