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[HTML][HTML] Regulation by small RNAs in bacteria: expanding frontiers
Research on the discovery and characterization of small, regulatory RNAs in bacteria has
exploded in recent years. These sRNAs act by base pairing with target mRNAs with which …
exploded in recent years. These sRNAs act by base pairing with target mRNAs with which …
Diversity, versatility and complexity of bacterial gene regulation mechanisms: opportunities and drawbacks for applications in synthetic biology
I Bervoets, D Charlier - FEMS microbiology reviews, 2019 - academic.oup.com
Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …
Global map** of small RNA-target interactions in bacteria
Small RNAs (sRNAs) associated with the RNA chaperon protein Hfq are key
posttranscriptional regulators of gene expression in bacteria. Deciphering the sRNA-target …
posttranscriptional regulators of gene expression in bacteria. Deciphering the sRNA-target …
An atlas of Hfq‐bound transcripts reveals 3′ UTRs as a genomic reservoir of regulatory small RNAs
The small RNAs associated with the protein Hfq constitute one of the largest classes of post‐
transcriptional regulators known to date. Most previously investigated members of this class …
transcriptional regulators known to date. Most previously investigated members of this class …
Small RNA interactome of pathogenic E. coli revealed through crosslinking of RNase E
RNA sequencing studies have identified hundreds of non‐coding RNA s in bacteria,
including regulatory small RNA (sRNA). However, our understanding of sRNA function has …
including regulatory small RNA (sRNA). However, our understanding of sRNA function has …
TargetRNA2: identifying targets of small regulatory RNAs in bacteria
Many small, noncoding RNAs (sRNAs) in bacteria act as posttranscriptional regulators of
messenger RNAs. TargetRNA2 is a web server that identifies mRNA targets of sRNA …
messenger RNAs. TargetRNA2 is a web server that identifies mRNA targets of sRNA …
Comparative Analysis of Regulatory Elements between Escherichia coli and Klebsiella pneumoniae by Genome-Wide Transcription Start Site Profiling
Genome-wide transcription start site (TSS) profiles of the enterobacteria Escherichia coli and
Klebsiella pneumoniae were experimentally determined through modified 5′ RACE …
Klebsiella pneumoniae were experimentally determined through modified 5′ RACE …
Probing the sRNA regulatory landscape of P. aeruginosa: post‐transcriptional control of determinants of pathogenicity and antibiotic susceptibility
During environmental adaptation bacteria use small regulatory RNAs (sRNAs) to repress or
activate expression of a large fraction of their proteome. We extended the use of the in vivo …
activate expression of a large fraction of their proteome. We extended the use of the in vivo …
Accelerating discovery and functional analysis of small RNAs with new technologies
Over the past decade, bacterial small RNAs (sRNAs) have gone from a biological curiosity to
being recognized as a major class of regulatory molecules. High-throughput methods for …
being recognized as a major class of regulatory molecules. High-throughput methods for …
How do base-pairing small RNAs evolve?
TB Updegrove, SA Shabalina… - FEMS microbiology …, 2015 - academic.oup.com
The increasing numbers of characterized base-pairing small RNAs (sRNAs) and the
identification of these regulators in a broad range of bacteria are allowing comparisons …
identification of these regulators in a broad range of bacteria are allowing comparisons …