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Long noncoding RNA in cancer: wiring signaling circuitry
C Lin, L Yang - Trends in cell biology, 2018 - cell.com
Long noncoding RNAs (lncRNAs), which are encoded by a vast less explored region of the
human genome, may hold missing drivers of cancer and have gained attention recently as a …
human genome, may hold missing drivers of cancer and have gained attention recently as a …
The role of long noncoding RNAs in neurodegenerative diseases
P Wan, W Su, Y Zhuo - Molecular neurobiology, 2017 - Springer
Long noncoding RNAs (lncRNAs) are transcripts with low protein-coding potential but
occupy a large part of transcriptional output. Their roles include regulating gene expression …
occupy a large part of transcriptional output. Their roles include regulating gene expression …
Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs
Advances in vertebrate genomics have uncovered thousands of loci encoding long
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory …
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory …
lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse
Long non-coding RNAs (lncRNAs) play key roles in various cellular contexts and diseases
by diverse mechanisms. With the rapid growth of identified lncRNAs and disease-associated …
by diverse mechanisms. With the rapid growth of identified lncRNAs and disease-associated …
Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer
Non-coding RNAs (ncRNAs) constitute a heterogeneous group of RNA molecules in terms
of biogenesis, biological function as well as length and structure. These biological …
of biogenesis, biological function as well as length and structure. These biological …
Simvastatin ameliorate memory deficits and inflammation in clinical and mouse model of Alzheimer's disease via modulating the expression of miR-106b
W Huang, Z Li, L Zhao, W Zhao - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Background Alzheimer's disease (AD) as a neurodegenerative brain disorder is a
devastating pathology leading to disastrous cognitive impairments and dementia, and …
devastating pathology leading to disastrous cognitive impairments and dementia, and …
Epigenetic memory: the Lamarckian brain
A Fischer - The EMBO journal, 2014 - embopress.org
Recent data support the view that epigenetic processes play a role in memory consolidation
and help to transmit acquired memories even across generations in a Lamarckian manner …
and help to transmit acquired memories even across generations in a Lamarckian manner …
[HTML][HTML] Long non-coding RNAs: novel targets for nervous system disease diagnosis and therapy
IA Qureshi, MF Mehler - Neurotherapeutics, 2013 - Elsevier
The human genome encodes tens of thousands of long non-coding RNAs (lncRNAs), a
novel and important class of genes. Our knowledge of lncRNAs has grown exponentially …
novel and important class of genes. Our knowledge of lncRNAs has grown exponentially …
Long non-coding RNAs, novel culprits, or bodyguards in neurodegenerative diseases
DQ Wang, P Fu, C Yao, LS Zhu, TY Hou… - … Therapy Nucleic Acids, 2018 - cell.com
Long non-coding RNA (lncRNA) is a kind of non-coding RNA (ncRNA), with a length of 200
nt to 100 kb, that lacks a significant open reading frame (ORF) encoding a protein. lncRNAs …
nt to 100 kb, that lacks a significant open reading frame (ORF) encoding a protein. lncRNAs …
[HTML][HTML] Genomic variations in non-coding RNAs: structure, function and regulation
The last decade has seen tremendous improvements in the understanding of human
variations and their association with human traits and diseases. The availability of high …
variations and their association with human traits and diseases. The availability of high …