Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

Brain endocannabinoid (eCB) signalling influences the motivation for natural rewards (such
as palatable food, sexual activity and social interaction) and modulates the rewarding effects …

Stress has a critical role in the development and expression of many psychiatric disorders,
and is a defining feature of posttraumatic stress disorder (PTSD). Stress also limits the …

The recent shift in sociopolitical debates and growing liberalization of cannabis use across
the globe has raised concern regarding its impact on vulnerable populations, such as …

Exposure to stress is an undeniable, but in most cases surmountable, part of life. However,
in certain individuals, exposure to severe or cumulative stressors can lead to an array of …

A review of the existing functional magnetic resonance imaging (fMRI) studies on reward
anticipation in patients with attention-deficit/hyperactivity disorder (ADHD) is provided. Meta …

The endocannabinoid (eCB) system has attracted attention for its role in various behavioral
and brain functions, and as a therapeutic target in neuropsychiatric disease states, including …

Preclinical and clinical studies implicate endocannabinoids (eCBs) in fear extinction, but the
underlying neural circuit basis of these actions is unclear. Here, we employed in vivo …

Background Posttraumatic stress disorder, an area of large unmet medical needs, is
characterized by persistence of fear memories and maladaptive stress responses. In …

Cross-species studies enable rapid translational discovery and produce the broadest impact
when both mechanism and phenotype are consistent across organisms. We developed a …