[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Z Pang, R Raudonis, BR Glick, TJ Lin, Z Cheng - Biotechnology advances, 2019 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

[HTML][HTML] Clinical impact of antibiotics for the treatment of Pseudomonas aeruginosa biofilm infections

E Olivares, S Badel-Berchoux, C Provot… - Frontiers in …, 2020 - frontiersin.org
Bacterial biofilms are highly recalcitrant to antibiotic therapies due to multiple tolerance
mechanisms. The involvement of Pseudomonas aeruginosa in a wide range of biofilm …

Exploiting quorum sensing to confuse bacterial pathogens

B LaSarre, MJ Federle - Microbiology and molecular biology …, 2013 - journals.asm.org
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms

T Rasamiravaka, Q Labtani, P Duez… - BioMed research …, 2015 - Wiley Online Library
P. aeruginosa is an opportunistic pathogenic bacterium responsible for both acute and
chronic infections. Beyond its natural resistance to many drugs, its ability to form biofilm, a …

[BUKU][B] Handbook of essential oils: science, technology, and applications

KHC Baser, G Buchbauer - 2009 - taylorfrancis.com
Egyptian hieroglyphs, Chinese scrolls, and Ayurvedic literature record physicians
administering aromatic oils to their patients. Today society looks to science to document …

Quercetin is an effective inhibitor of quorum sensing, biofilm formation and virulence factors in Pseudomonas aeruginosa

J Ouyang, F Sun, W Feng, Y Sun, X Qiu… - Journal of applied …, 2016 - academic.oup.com
Aims The study aimed to perform a systematic investigation of the effects of quercetin on
biofilm formation and virulence factors in Pseudomonas aeruginosa. Methods and Results …

Aspirin is an efficient inhibitor of quorum sensing, virulence and toxins in Pseudomonas aeruginosa

SA El-Mowafy, KH Abd El Galil, SM El-Messery… - Microbial …, 2014 - Elsevier
Quorum sensing (QS) plays a vital role in regulation of virulence factors and toxins in
Pseudomonas aeruginosa, which can cause serious human infections. Therefore, the QS …

Inhibition of Pseudomonas aeruginosa quorum sensing by subinhibitory concentrations of curcumin with gentamicin and azithromycin

S Bahari, H Zeighami, H Mirshahabi… - Journal of global …, 2017 - Elsevier
Objectives Pseudomonas aeruginosa quorum sensing (QS) circuits regulate virulence
factors and co-ordinate bacterial pathogenicity. This study aimed to investigate the inhibitory …

Quorum quenching: A potential target for antipseudomonal therapy

F Hemmati, R Salehi, R Ghotaslou… - Infection and Drug …, 2020 - Taylor & Francis
There has been excessive rate of use of antibiotics to fight Pseudomonas aeruginosa (P.
aeruginosa) infections worldwide, which has consequently caused the increased resistance …

Quantitative Proteomics Reveals the Mechanism of Silver Nanoparticles against Multidrug-Resistant Pseudomonas aeruginosa Biofilms

Y Zhang, X Pan, S Liao, C Jiang, L Wang… - Journal of proteome …, 2020 - ACS Publications
The decline of clinically effective antibiotics has made it necessary to develop more effective
antimicrobial agents, especially for refractory biofilm-related infections. Silver nanoparticles …