The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

A growing literature suggests that exposure to adverse social conditions may accelerate
biological aging, offering one mechanism through which adversity may increase risk for age …

INTRODUCTION To date, 559 humans have been flown into space, but long-duration (> 300
days) missions are rare (n= 8 total). Long-duration missions that will take humans to Mars …

Improved methods to measure the shortest (not just average) telomere lengths (TLs) are
needed. We developed Telomere Shortest Length Assay (TeSLA), a technique that detects …

Background Leukocyte telomere length (LTL) is a putative biological marker of immune
system age, and there are demonstrated associations between LTL and cardiovascular …

The prediction that telomere length (TL) shortens with increasing age is a major element in
considering the role of telomeres as a key player in evolution. While telomere attrition is …

Aging is associated with complex biological changes that can be accelerated, slowed, or
even temporarily reversed by biological and non-biological factors. This article focuses on …

Telomeres play an important part in aging and show relationships to lifetime adversity,
particularly childhood adversity. Meta-analyses demonstrate reliable associations between …

Abstract Purpose of Review Recognize which are the elements that predict why a person is
aging faster or slower and which intervention we can arrange to slow down the process …

Study design Family members caring for chronically ill relatives are typically sedentary,
chronically stressed, and at high risk of disease. Observational reports suggest caregivers …