Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Antimicrobial host defense peptides are produced by all complex organisms as well as
some microbes and have diverse and complex antimicrobial activities. Collectively these …

Antibiotic resistance is spreading faster than the introduction of new compounds into clinical
practice, causing a public health crisis. Most antibiotics were produced by screening soil …

The endospore‐forming rhizobacterium Bacillus subtilis–the model system for Gram‐
positive organisms, is able to produce more than two dozen antibiotics with an amazing …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a promising
source of new antimicrobials in the face of rising antibiotic resistance. Here, we report a …

Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host
defenses against potential harmful encounters in their surroundings. AMPs are short …

Members of the genus Bacillus are known to produce a wide arsenal of antimicrobial
substances, including peptide and lipopeptide antibiotics, and bacteriocins. Many of the …

Unlike numerous pore-forming amphiphilic peptide antibiotics, the lantibiotic nisin is active
in nanomolar concentrations, which results from its ability to use the lipid-bound cell wall …

Resistance to antibiotics is increasing in some groups of clinically important pathogens. For
instance, high vancomycin resistance has emerged in enterococci. Promising alternative …

The lantibiotics are a group of ribosomally synthesised, post-translationally modified
peptides containing unusual amino acids, such as dehydrated and lanthionine residues …