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Microbiota–host communications: Bacterial extracellular vesicles as a common language
RA Ñahui Palomino, C Vanpouille, PE Costantini… - PLoS …, 2021 - journals.plos.org
Both gram-negative and gram-positive bacteria release extracellular vesicles (EVs) that
contain components from their mother cells. Bacterial EVs are similar in size to mammalian …
contain components from their mother cells. Bacterial EVs are similar in size to mammalian …
Understanding modern-day vaccines: what you need to know
V Vetter, G Denizer, LR Friedland, J Krishnan… - Annals of …, 2018 - Taylor & Francis
Vaccines are considered to be one of the greatest public health achievements of the last
century. Depending on the biology of the infection, the disease to be prevented, and the …
century. Depending on the biology of the infection, the disease to be prevented, and the …
Clinical translation of extracellular vesicles
Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …
Twenty years of bacterial genome sequencing
Twenty years ago, the publication of the first bacterial genome sequence, from Haemophilus
influenzae, shook the world of bacteriology. In this Timeline, we review the first two decades …
influenzae, shook the world of bacteriology. In this Timeline, we review the first two decades …
Effectiveness and impact of a reduced infant schedule of 4CMenB vaccine against group B meningococcal disease in England: a national observational cohort study
SR Parikh, NJ Andrews, K Beebeejaun, H Campbell… - The Lancet, 2016 - thelancet.com
Summary Background In September, 2015, the UK became the first country to introduce the
multicomponent group B meningococcal (MenB) vaccine (4CMenB, Bexsero) into a publicly …
multicomponent group B meningococcal (MenB) vaccine (4CMenB, Bexsero) into a publicly …
Vaxign-ML: supervised machine learning reverse vaccinology model for improved prediction of bacterial protective antigens
E Ong, H Wang, MU Wong, M Seetharaman… - …, 2020 - academic.oup.com
Motivation Reverse vaccinology (RV) is a milestone in rational vaccine design, and machine
learning (ML) has been applied to enhance the accuracy of RV prediction. However, ML …
learning (ML) has been applied to enhance the accuracy of RV prediction. However, ML …
A review of reverse vaccinology approaches for the development of vaccines against ticks and tick borne diseases
AE Lew-Tabor, MR Valle - Ticks and tick-borne diseases, 2016 - Elsevier
The field of reverse vaccinology developed as an outcome of the genome sequence
revolution. Following the introduction of live vaccinations in the western world by Edward …
revolution. Following the introduction of live vaccinations in the western world by Edward …
Emerging technologies for low‐cost, rapid vaccine manufacture
To stop the spread of future epidemics and meet infant vaccination demands in low‐and
middle‐income countries, flexible, rapid and low‐cost vaccine development and …
middle‐income countries, flexible, rapid and low‐cost vaccine development and …
Genetically engineered cellular nanoparticles for biomedical applications
N Krishnan, FX Peng, A Mohapatra, RH Fang, L Zhang - Biomaterials, 2023 - Elsevier
In recent years, nanoparticles derived from cellular membranes have been increasingly
explored for the prevention and treatment of human disease. With their flexible design and …
explored for the prevention and treatment of human disease. With their flexible design and …
Extracellular vesicles as antigen carriers for novel vaccination avenues
M Mehanny, CM Lehr, G Fuhrmann - Advanced drug delivery reviews, 2021 - Elsevier
Antigen delivery has always been a challenge in scientific practice of vaccine formulation.
Yet, mammalian extracellular vesicles (EVs) or bacterial membrane vesicles (MVs) provide …
Yet, mammalian extracellular vesicles (EVs) or bacterial membrane vesicles (MVs) provide …