Estrogens control a variety of physiological and disease-linked processes, most notably
reproduction, bone remodeling and breast cancer, and their effects are transduced through …

The brain has the highest mitochondrial energy demand of any organ. Therefore, subtle
changes in mitochondrial energy production will preferentially affect the brain. Considerable …

Bisphenol A (BPA) is an estrogenic endocrine disruptor widely used in the production of
plastics. Increasing evidence indicates that in utero BPA exposure affects sexual …

Background Various lines of evidence have shown that bisphenol A [BPA; HO-C6H4-C
(CH3) 2-C6H4-OH] acts as an endocrine disruptor when present in very low doses. We have …

Bisphenol A (BPA) has been acknowledged as an estrogenic chemical able to interact with
human estrogen receptors (ER). Many lines of evidence reveal that BPA has an impact as …

In addition to their well-known role in the female reproductive system, estrogens can act in
the brain to regulate a wide range of behaviors and physiological functions in both sexes …

Estrogen receptor-related receptors (ERRs; α, β, γ) are orphan nuclear receptors and
constitutively active without binding to estrogen. Like estrogen receptors (ERs), ERRs bind …

While estrogens are well known for their pivotal role in the female reproductive system, they
also play a crucial function in regulating physiological processes associated with learning …

Concerns have been raised regarding the long-term impacts of early life exposure to the
ubiquitous environmental contaminant bisphenol A (BPA) on brain organization. Because …

Sle1c is a sublocus of the NZM2410-derived Sle1 major lupus susceptibility locus. We have
shown previously that Sle1c contributes to lupus pathogenesis by conferring increased …