Membrane lipids: where they are and how they behave
Throughout the biological world, a 30 Å hydrophobic film typically delimits the environments
that serve as the margin between life and death for individual cells. Biochemical and …
that serve as the margin between life and death for individual cells. Biochemical and …
Phospholipid membranes as chemically and functionally tunable materials
The sheet‐like lipid bilayer is the fundamental structural component of all cell membranes.
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …
ATP13A2 deficiency disrupts lysosomal polyamine export
Abstract ATP13A2 (PARK9) is a late endolysosomal transporter that is genetically implicated
in a spectrum of neurodegenerative disorders, including Kufor-Rakeb syndrome—a …
in a spectrum of neurodegenerative disorders, including Kufor-Rakeb syndrome—a …
Lipid polymorphisms and membrane shape
VA Frolov, AV Shnyrova… - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Morphological plasticity of biological membrane is critical for cellular life, as cells need to
quickly rearrange their membranes. Yet, these rearrangements are constrained in two ways …
quickly rearrange their membranes. Yet, these rearrangements are constrained in two ways …
Pre-and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis
D Halter, S Neumann, SM van Dijk… - The Journal of cell …, 2007 - rupress.org
Glycosphingolipids are controlled by the spatial organization of their metabolism and by
transport specificity. Using immunoelectron microscopy, we localize to the Golgi stack the …
transport specificity. Using immunoelectron microscopy, we localize to the Golgi stack the …
[HTML][HTML] How lipid flippases can modulate membrane structure
PF Devaux, A Herrmann, N Ohlwein… - Biochimica et Biophysica …, 2008 - Elsevier
Phospholipid flippases, are proteins able to translocate phospholipids from one side of a
membrane to the other even against a gradient of concentration and thereby able to …
membrane to the other even against a gradient of concentration and thereby able to …
Membrane protein reconstitution into giant unilamellar vesicles: a review on current techniques
IL Jørgensen, GC Kemmer, TG Pomorski - European Biophysics Journal, 2017 - Springer
Studying membrane proteins at the molecular level represents a major challenge in
biochemistry due to the complexity of the membrane in which they are embedded. As an …
biochemistry due to the complexity of the membrane in which they are embedded. As an …
Shape dynamics, lipid hydrodynamics, and the complex viscoelasticity of bilayer membranes
Biological membranes are continuously brought out of equilibrium, as they shape
organelles, package and transport cargo, or respond to external actions. Even the dynamics …
organelles, package and transport cargo, or respond to external actions. Even the dynamics …
Unveiling the active nature of living-membrane fluctuations and mechanics
Soft-condensed matter physics has provided, in the past decades, many of the relevant
concepts and methods allowing successful description of living cells and biological tissues …
concepts and methods allowing successful description of living cells and biological tissues …
[HTML][HTML] Giant unilamellar vesicles containing phosphatidylinositol (4, 5) bisphosphate: characterization and functionality
Biomimetic systems such as giant unilamellar vesicles (GUVs) are increasingly used for
studying protein/lipid interactions due to their size (similar to that of cells) and to their ease of …
studying protein/lipid interactions due to their size (similar to that of cells) and to their ease of …