Cell-substrate interactions play a crucial role in the design of better biomaterials and
integration of implants with the tissues. Adhesion is the binding process of the cells to the …

During recent decades vast and continuously increasing numbers of biomedical implants
have been introduced for continuous use in the human body. Since the early cemented hip …

In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Titanium (Ti) osseointegration is critical for the success of dental and orthopedic implants.
Previous studies have shown that surface roughness at the micro-and submicro-scales …

Cells are inherently sensitive to local mesoscale, microscale, and nanoscale patterns of
chemistry and topography. We review current approaches to control cell behavior through …

The interaction of mammalian cells with nanoscale topography has proven to be an
important signaling modality in controlling cell function. Naturally occurring nanotopographic …

We generated, on titanium surfaces, self-assembled layers of vertically oriented TiO2
nanotubes with defined diameters between 15 and 100 nm and show that adhesion …

Eliminating bacterial infection and simultaneously providing a bioactive environment for
bone growth during treatment of severe osteomyelitis is one of the greatest global …

The nanoscale surface topography of artificial materials is known to play a significant role in
interactions with biological systems such as proteins and cells. A detailed understanding …

Cell alignment plays a critical role in various cell behaviors including cytoskeleton
reorganization, membrane protein relocation, nucleus gene expression, and ECM …