The key initiating process in atherogenesis is the subendothelial retention of apolipoprotein
B–containing lipoproteins. Local biological responses to these retained lipoproteins …

The recognition that the increase of plasma triglyceride rich lipoproteins (TRLs) is
associated with multiple alterations of other lipoproteins species that are potentially …

Their strategic location between blood and tissue and their constitutive properties allow
endothelial cells (EC) to monitor the transport of plasma molecules, by employing …

Due to the fact that one of the main causes of worldwide deaths are directly related to
atherosclerosis, scientists are constantly looking for atherosclerotic factors, in an attempt to …

It is well established that inflammation is an integral feature of atherosclerosis and of the
cardiovascular diseases which it underlies. Oxidative stress is also recognized as a key …

The classical regard of lipid droplets as mere static energy-storage organelles has evolved
dramatically. Nowadays these organelles are known to participate in key processes of cell …

Lipoprotein subclass measurements may enhance the prediction of coronary artery disease
(CAD) risk, but clinical application of such information has been hindered by the relatively …

Certain members of the phospholipase A2 superfamily of enzymes have established causal
involvement in atherosclerosis, thus at least two groups of this family of enzymes have been …

In humans, a chronically increased circulating level of C-reactive protein (CRP), a positive
acute-phase reactant, is an independent risk factor for cardiovascular disease. This …

Secretory phospholipase A2 (PLA2) can be proatherogenic both in the circulation and in the
arterial wall. In blood plasma, PLA2 can modify the circulating lipoproteins and so induce …