Glucosinolates from cruciferous vegetables and their potential role in chronic disease: Investigating the preclinical and clinical evidence

EL Connolly, M Sim, N Travica, W Marx… - Frontiers in …, 2021 - frontiersin.org
An increasing body of evidence highlights the strong potential for a diet rich in fruit and
vegetables to delay, and often prevent, the onset of chronic diseases, including …

Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives

DM Tanase, EM Gosav, MI Anton, M Floria… - Biomolecules, 2022 - mdpi.com
Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …

[HTML][HTML] Phytochemicals that act on synaptic plasticity as potential prophylaxis against stress-induced depressive disorder

S Yoon, H Iqbal, SM Kim, M ** - Biomolecules & Therapeutics, 2023 - ncbi.nlm.nih.gov
Depression is a neuropsychiatric disorder associated with persistent stress and disruption of
neuronal function. Persistent stress causes neuronal atrophy, including loss of synapses …

Nordic diet and its benefits in neurological function: a systematic review of observational and intervention studies

RS Jafari, V Behrouz - Frontiers in Nutrition, 2023 - frontiersin.org
Introduction Neurological disorders have been considered the major contributors to global
long-term disability and lower quality of life. Lifestyle factors, such as dietary patterns, are …

The role of nutrients in human neurodevelopment and their potential to prevent neurodevelopmental adversity

S Heland, N Fields, SJ Ellery, M Fahey… - Frontiers in Nutrition, 2022 - frontiersin.org
Nutritional deficits or excesses affect a huge proportion of pregnant women worldwide.
Maternal nutrition has a significant influence on the fetal environment and can dramatically …

The role of isothiocyanate-rich plants and supplements in neuropsychiatric disorders: A review and update

M Ramakrishnan, JW Fahey, AW Zimmerman… - Frontiers in …, 2024 - frontiersin.org
Neuroinflammation in response to environmental stressors is an important common pathway
in a number of neurological and psychiatric disorders. Responses to immune-mediated …

Exploring the anti‐inflammatory activity of sulforaphane

K Treasure, J Harris… - Immunology and Cell …, 2023 - Wiley Online Library
Dysregulation of innate immune responses can result in chronic inflammatory conditions.
Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but …

The NLRP3 Inflammasome as a Pathogenic Player Showing Therapeutic Potential in Rheumatoid Arthritis and Its Comorbidities: A Narrative Review

PK Chen, KT Tang, DY Chen - International Journal of Molecular …, 2024 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by chronic
synovitis and the progressive destruction of cartilage and bone. RA is commonly …

Effect of sulforaphane on testicular ischemia-reperfusion injury induced by testicular torsion-detorsion in rats

SM Wei, YM Huang - Scientific Reports, 2024 - nature.com
Testicular ischemia-reperfusion induces enhanced concentration of reactive oxygen
species. The increased reactive oxygen species harm cellular lipids, nucleic acids, proteins …

Therapeutic potential of sulforaphane in liver diseases: a review

L Yan, Y Yan - Frontiers in Pharmacology, 2023 - frontiersin.org
The burden of liver diseases such as metabolic-associated fatty liver diseases and
hepatocellular carcinoma has increased rapidly worldwide over the past decades. However …