Toll-like receptors—taking an evolutionary approach
F Leulier, B Lemaitre - Nature Reviews Genetics, 2008 - nature.com
The Toll receptor was initially identified in Drosophila melanogaster for its role in embryonic
development. Subsequently, D. melanogaster Toll and mammalian Toll-like receptors …
development. Subsequently, D. melanogaster Toll and mammalian Toll-like receptors …
Genetic architecture of quantitative traits in mice, flies, and humans
J Flint, TFC Mackay - Genome research, 2009 - genome.cshlp.org
We compare and contrast the genetic architecture of quantitative phenotypes in two
genetically well-characterized model organisms, the laboratory mouse, Mus musculus, and …
genetically well-characterized model organisms, the laboratory mouse, Mus musculus, and …
Bacterial Communities of Diverse Drosophila Species: Ecological Context of a Host–Microbe Model System
Drosophila melanogaster is emerging as an important model of non-pathogenic host–
microbe interactions. The genetic and experimental tractability of Drosophila has led to …
microbe interactions. The genetic and experimental tractability of Drosophila has led to …
[LIBRO][B] Mechanisms of life history evolution: the genetics and physiology of life history traits and trade-offs
Life history theory seeks to explain the evolution of the major features of life cycles by
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …
Immunity in a variable world
BP Lazzaro, TJ Little - … of the Royal Society B: Biological …, 2009 - royalsocietypublishing.org
Immune function is likely to be a critical determinant of an organism's fitness, yet most
natural animal and plant populations exhibit tremendous genetic variation for immune traits …
natural animal and plant populations exhibit tremendous genetic variation for immune traits …
The bee microbiome: impact on bee health and model for evolution and ecology of host-microbe interactions
As pollinators, bees are cornerstones for terrestrial ecosystem stability and key components
in agricultural productivity. All animals, including bees, are associated with a diverse …
in agricultural productivity. All animals, including bees, are associated with a diverse …
Host Species and Environmental Effects on Bacterial Communities Associated with Drosophila in the Laboratory and in the Natural Environment
The fruit fly Drosophila is a classic model organism to study adaptation as well as the
relationship between genetic variation and phenotypes. Although associated bacterial …
relationship between genetic variation and phenotypes. Although associated bacterial …
Fitness consequences of immune responses: strengthening the empirical framework for ecoimmunology
AL Graham, DM Shuker, LC Pollitt… - Functional …, 2011 - Wiley Online Library
Ecoimmunologists aim to understand the costs, benefits, and net fitness consequences of
different strategies for immune defense. 2. Measuring the fitness consequences of immune …
different strategies for immune defense. 2. Measuring the fitness consequences of immune …
Introduction. ecological immunology
An organism's fitness is critically reliant on its immune system to provide protection against
parasites and pathogens. The structure of even simple immune systems is surprisingly …
parasites and pathogens. The structure of even simple immune systems is surprisingly …
Insect immune resistance to parasitoids
Insect host—parasitoid interactions involve complex physiological, biochemical and genetic
interactions. Against endoparasitoids, immune‐competent hosts initiate a blood cell …
interactions. Against endoparasitoids, immune‐competent hosts initiate a blood cell …