Toll-like receptors—taking an evolutionary approach

F Leulier, B Lemaitre - Nature Reviews Genetics, 2008 - nature.com
The Toll receptor was initially identified in Drosophila melanogaster for its role in embryonic
development. Subsequently, D. melanogaster Toll and mammalian Toll-like receptors …

Genetic architecture of quantitative traits in mice, flies, and humans

J Flint, TFC Mackay - Genome research, 2009 - genome.cshlp.org
We compare and contrast the genetic architecture of quantitative phenotypes in two
genetically well-characterized model organisms, the laboratory mouse, Mus musculus, and …

Bacterial Communities of Diverse Drosophila Species: Ecological Context of a Host–Microbe Model System

JA Chandler, J Morgan Lang, S Bhatnagar… - PLoS …, 2011 - journals.plos.org
Drosophila melanogaster is emerging as an important model of non-pathogenic host–
microbe interactions. The genetic and experimental tractability of Drosophila has led to …

[LIBRO][B] Mechanisms of life history evolution: the genetics and physiology of life history traits and trade-offs

T Flatt, A Heyland - 2011 - books.google.com
Life history theory seeks to explain the evolution of the major features of life cycles by
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …

Immunity in a variable world

BP Lazzaro, TJ Little - … of the Royal Society B: Biological …, 2009 - royalsocietypublishing.org
Immune function is likely to be a critical determinant of an organism's fitness, yet most
natural animal and plant populations exhibit tremendous genetic variation for immune traits …

The bee microbiome: impact on bee health and model for evolution and ecology of host-microbe interactions

P Engel, WK Kwong, Q McFrederick, KE Anderson… - MBio, 2016 - Am Soc Microbiol
As pollinators, bees are cornerstones for terrestrial ecosystem stability and key components
in agricultural productivity. All animals, including bees, are associated with a diverse …

Host Species and Environmental Effects on Bacterial Communities Associated with Drosophila in the Laboratory and in the Natural Environment

F Staubach, JF Baines, S Künzel, EM Bik, DA Petrov - PloS one, 2013 - journals.plos.org
The fruit fly Drosophila is a classic model organism to study adaptation as well as the
relationship between genetic variation and phenotypes. Although associated bacterial …

Fitness consequences of immune responses: strengthening the empirical framework for ecoimmunology

AL Graham, DM Shuker, LC Pollitt… - Functional …, 2011 - Wiley Online Library
Ecoimmunologists aim to understand the costs, benefits, and net fitness consequences of
different strategies for immune defense. 2. Measuring the fitness consequences of immune …

Introduction. ecological immunology

H Schulenburg, J Kurtz, Y Moret… - … Transactions of the …, 2009 - royalsocietypublishing.org
An organism's fitness is critically reliant on its immune system to provide protection against
parasites and pathogens. The structure of even simple immune systems is surprisingly …

Insect immune resistance to parasitoids

Y Carton, M Poirié, AJ Nappi - Insect Science, 2008 - Wiley Online Library
Insect host—parasitoid interactions involve complex physiological, biochemical and genetic
interactions. Against endoparasitoids, immune‐competent hosts initiate a blood cell …