Congenital diaphragmatic hernia

R Keijzer, P Puri - Seminars in pediatric surgery, 2010 - Elsevier
Congenital diaphragmatic hernia (CDH) is a congenital anomaly consisting of a
posterolateral defect in the diaphragm also known as a Bochdalek hernia. It occurs in 1 in …

Congenital diaphragmatic hernia

JA Tovar - Orphanet journal of rare diseases, 2012 - Springer
Abstract Congenital Diaphragmatic Hernia (CDH) is defined by the presence of an orifice in
the diaphragm, more often left and posterolateral that permits the herniation of abdominal …

Dual-hit hypothesis explains pulmonary hypoplasia in the nitrofen model of congenital diaphragmatic hernia

R Keijzer, J Liu, J Deimling, D Tibboel… - The American journal of …, 2000 - Elsevier
Pulmonary hypoplasia associated with congenital diaphragmatic hernia (CDH) remains a
major therapeutic problem. Moreover, the pathogenesis of pulmonary hypoplasia in case of …

Development of the diaphragm–a skeletal muscle essential for mammalian respiration

AJ Merrell, G Kardon - The FEBS journal, 2013 - Wiley Online Library
The mammalian diaphragm muscle is essential for respiration, and thus is one of the most
critical skeletal muscles in the human body. Defects in diaphragm development leading to …

Genetic factors in congenital diaphragmatic hernia

AM Holder, M Klaassens, D Tibboel, A de Klein… - The American Journal of …, 2007 - cell.com
Congenital diaphragmatic hernia (CDH) is a relatively common birth defect associated with
high mortality and morbidity. Although the exact etiology of most cases of CDH remains …

Congenital diaphragmatic hernia

L Leeuwen, DA Fitzgerald - Journal of paediatrics and child …, 2014 - Wiley Online Library
Congenital diaphragmatic hernia is an uncommon congenital anomaly of the diaphragm
with pulmonary hypoplasia and persistent pulmonary hypertension as serious …

Etiology of congenital diaphragmatic hernia: the retinoid hypothesis

JJ Greer, RP Babiuk, B Thebaud - Pediatric research, 2003 - nature.com
Congenital diaphragmatic hernia (CDH) is a major life-threatening cause of respiratory
failure in the newborn. Although significant efforts have been undertaken to unravel the …

Embryological origins and development of the rat diaphragm

RP Babiuk, W Zhang, R Clugston… - Journal of …, 2003 - Wiley Online Library
Textbooks of embryology provide a standard set of drawings and text reflecting the
traditional interpretation of phrenic nerve and diaphragm development based on anatomical …

Current concepts on the pathogenesis and etiology of congenital diaphragmatic hernia

JJ Greer - Respiratory Physiology & Neurobiology, 2013 - Elsevier
This review outlines research that has advanced our understanding of the pathogenesis and
etiology of congenital diaphragmatic hernia (CDH). The majority of CDH cases involve …

Teratogen-induced, dietary and genetic models of congenital diaphragmatic hernia share a common mechanism of pathogenesis

RD Clugston, J Klattig, C Englert… - The American journal of …, 2006 - Elsevier
Congenital diaphragmatic hernia (CDH) is a frequently occurring, major congenital
abnormality that has high mortality and significant morbidity in survivors. Currently, the …