Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man

RJ Fenster, LAM Lebois, KJ Ressler… - Nature Reviews …, 2018 - nature.com
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …

The role of the locus coeruleus in the generation of pathological anxiety

LS Morris, JG McCall, DS Charney… - Brain and …, 2020 - journals.sagepub.com
This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

The role of the medial prefrontal cortex in the conditioning and extinction of fear

TF Giustino, S Maren - Frontiers in behavioral neuroscience, 2015 - frontiersin.org
Once acquired, a fearful memory can persist for a lifetime. Although learned fear can be
extinguished, extinction memories are fragile. The resilience of fear memories to extinction …

The neurocircuitry of fear, stress, and anxiety disorders

LM Shin, I Liberzon - Neuropsychopharmacology, 2010 - nature.com
Anxiety disorders are a significant problem in the community, and recent neuroimaging
research has focused on determining the brain circuits that underlie them. Research on the …

Fear extinction as a model for translational neuroscience: ten years of progress

MR Milad, GJ Quirk - Annual review of psychology, 2012 - annualreviews.org
The psychology of extinction has been studied for decades. Approximately 10 years ago,
however, there began a concerted effort to understand the neural circuits of extinction of fear …

Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia

A Etkin, TD Wager - American journal of Psychiatry, 2007 - Am Psychiatric Assoc
Objective: The study of human anxiety disorders has benefited greatly from functional
neuroimaging approaches. Individual studies, however, vary greatly in their findings. The …

Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI

KL Phan, T Wager, SF Taylor, I Liberzon - Neuroimage, 2002 - Elsevier
Neuroimagingstudies with positron emission tomography (PET) and functional magnetic
resonance imaging (fMRI) have begun to describe the functional neuroanatomy of emotion …

[書籍][B] Synaptic self: How our brains become who we are

J LeDoux - 2003 - books.google.com
In 1996 Joseph LeDoux's The Emotional Brain presented a revelatory examination of the
biological bases of our emotions and memories. Now, the world-renowned expert on the …

[書籍][B] Affect dysregulation and disorders of the self (Norton Series on Interpersonal Neurobiology)

A Schore - 2003 - books.google.com
This volume (one of two) is the first presentation of Schore's comprehensive theory in book
form, as it has developed since 1994. In 1994 Allan Schore published his groundbreaking …

Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress

DS Charney - American journal of Psychiatry, 2004 - Am Psychiatric Assoc
OBJECTIVE: Most research on the effects of severe psychological stress has focused on
stress-related psychopathology. Here, the author develops psychobiological models of …