[HTML][HTML] Selective autophagy of intracellular organelles: recent research advances
Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and …
that degrades over-abundant or damaged organelles, large protein aggregates and …
Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae
M Conrad, J Schothorst, HN Kankipati… - FEMS microbiology …, 2014 - academic.oup.com
The yeast Saccharomyces cerevisiae has been a favorite organism for pioneering studies
on nutrient-sensing and signaling mechanisms. Many specific nutrient responses have been …
on nutrient-sensing and signaling mechanisms. Many specific nutrient responses have been …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
TOR signaling and nutrient sensing
All living organisms rely on nutrients to sustain cell metabolism and energy production,
which in turn need to be adjusted based on available resources. The evolutionarily …
which in turn need to be adjusted based on available resources. The evolutionarily …
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
J Guevara-Aguirre, P Balasubramanian… - Science translational …, 2011 - science.org
Mutations in growth signaling pathways extend life span, as well as protect against age-
dependent DNA damage in yeast and decrease insulin resistance and cancer in mice. To …
dependent DNA damage in yeast and decrease insulin resistance and cancer in mice. To …
An overview of the molecular mechanism of autophagy
Autophagy is a highly conserved cellular degradation process in which portions of cytosol
and organelles are sequestered into a double-membrane vesicle, an autophagosome, and …
and organelles are sequestered into a double-membrane vesicle, an autophagosome, and …