Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

The human mycobiome: colonization, composition and the role in health and disease

P Belvoncikova, P Splichalova, P Videnska, R Gardlik - Journal of Fungi, 2022 - mdpi.com
The mycobiome is the fungal component of the human microbial ecosystem that represents
only a small part of this environment but plays an essential role in maintaining homeostasis …

Pathogenicity and virulence of Aspergillus fumigatus

K Earle, C Valero, DP Conn, G Vere, PC Cook… - Virulence, 2023 - Taylor & Francis
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

On the lineage of Aspergillus fumigatus isolates in common laboratory use

M Bertuzzi, N Van Rhijn, S Krappmann… - Medical …, 2021 - academic.oup.com
The origin of isolates routinely used by the community of Aspergillus fumigatus researchers
is periodically a matter of intense discussion at our centre, as the construction of …

Role of mitophagy in regulating intestinal oxidative damage

X Wen, L Tang, R Zhong, L Liu, L Chen, H Zhang - Antioxidants, 2023 - mdpi.com
The mitochondrion is also a major site for maintaining redox homeostasis between reactive
oxygen species (ROS) generation and scavenging. The quantity, quality, and functional …

New perspectives in the diagnosis and management of allergic fungal airway disease

AJ Wardlaw, EM Rick, L Pur Ozyigit… - Journal of Asthma …, 2021 - Taylor & Francis
Allergy to airway-colonising, thermotolerant, filamentous fungi represents a distinct
eosinophilic endotype of often severe lung disease. This endotype, which particularly affects …

Retinoids in fungal infections: From bench to bedside

T Cosio, R Gaziano, G Zuccari, G Costanza, S Grelli… - Pharmaceuticals, 2021 - mdpi.com
Retinoids—a class of chemical compounds derived from vitamin A or chemically related to it—
are used especially in dermatology, oncohematology and infectious diseases. It has been …

Relationship between Aspergillus and asthma

R Agarwal, V Muthu, IS Sehgal - Allergology International, 2023 - jstage.jst.go.jp
abstract Fungal sensitization is highly prevalent in severe asthma. The relationship between
fungus and asthma, especially Aspergillus fumigatus, has been the subject of extensive …

Striking back against fungal infections: The utilization of nanosystems for antifungal strategies

W Du, Y Gao, L Liu, S Sai, C Ding - International Journal of Molecular …, 2021 - mdpi.com
Fungal infections have become a major health concern, given that invasive infections by
Candida, Cryptococcus, and Aspergillus species have led to millions of mortalities …

Novel treatment approach for aspergilloses by targeting germination

K Verburg, J van Neer, M Duca, H de Cock - Journal of Fungi, 2022 - mdpi.com
Germination of conidia is an essential process within the Aspergillus life cycle and plays a
major role during the infection of hosts. Conidia are able to avoid detection by the majority of …