Pathophysiology of diabetes: An overview

MZ Banday, AS Sameer, S Nissar - Avicenna journal of …, 2020 - thieme-connect.com
Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex
pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which …

Monogenic diabetes

A Bonnefond, R Unnikrishnan, A Doria… - Nature Reviews …, 2023 - nature.com
Monogenic diabetes includes several clinical conditions generally characterized by early-
onset diabetes, such as neonatal diabetes, maturity-onset diabetes of the young (MODY) …

Revisiting astrocyte to neuron conversion with lineage tracing in vivo

LL Wang, C Serrano, X Zhong, S Ma, Y Zou, CL Zhang - Cell, 2021 - cell.com
In vivo cell fate conversions have emerged as potential regeneration-based therapeutics for
injury and disease. Recent studies reported that ectopic expression or knockdown of certain …

Report of the Committee on the classification and diagnostic criteria of diabetes mellitus: The Committee of the Japan Diabetes Society on the diagnostic criteria of …

Y Seino, K Nanjo, N Tajima, T Kadowaki, A Kashiwagi… - 2010 - Springer
Diabetes mellitus is a group of diseases associated with various metabolic disorders, the
main feature of which is chronic hyperglycemia due to insufficient insulin action. Its …

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

SS Fajans, GI Bell, KS Polonsky - New England Journal of …, 2001 - Mass Medical Soc
Maturity-onset diabetes of the young (MODY) is a clinically heterogeneous group of
disorders characterized by nonketotic diabetes mellitus, an autosomal dominant mode of …

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

Y Horikawa, N Oda, NJ Cox, X Li, M Orho-Melander… - Nature …, 2000 - nature.com
Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of
diabetes worldwide, affecting approximately 4% of the world's adult population. It is …

Maturity-onset diabetes of the young (MODY): current perspectives on diagnosis and treatment

T Urakami - Diabetes, metabolic syndrome and obesity: targets and …, 2019 - Taylor & Francis
Maturity-onset diabetes of the young (MODY) is characterized by autosomal dominant
inheritance, onset before 25 years of age, absence of β-cell autoimmunity, and sustained …

The epidemiology, molecular pathogenesis, diagnosis, and treatment of maturity-onset diabetes of the young (MODY)

KM Nkonge, DK Nkonge, TN Nkonge - Clinical Diabetes and …, 2020 - Springer
Background The most common type of monogenic diabetes is maturity-onset diabetes of the
young (MODY), a clinically and genetically heterogeneous group of endocrine disorders that …

Zebrafish as a model for obesity and diabetes

L Zang, LA Maddison, W Chen - Frontiers in cell and developmental …, 2018 - frontiersin.org
Obesity and diabetes now considered global epidemics. The prevalence rates of diabetes
are increasing in parallel with the rates of obesity and the strong connection between these …

Epigenetics: a molecular link between environmental factors and type 2 diabetes

C Ling, L Groop - Diabetes, 2009 - Am Diabetes Assoc
Although obesity, reduced physical activity, and aging increase susceptibility to type 2
diabetes, many people exposed to these risk factors do not develop the disease. Recent …