Proteomics in antibiotic resistance and tolerance research: map** the resistome and the tolerome of bacterial pathogens

JE Sulaiman, H Lam - Proteomics, 2022 - Wiley Online Library
Antibiotic resistance, the ability of a microbial pathogen to evade the effects of antibiotics
thereby allowing them to grow under elevated drug concentrations, is an alarming health …

Proteomic and metabolomic profiling of methicillin resistant versus methicillin sensitive Staphylococcus aureus using a simultaneous extraction protocol

S Boucherabine, A Giddey, R Nassar… - Frontiers in …, 2024 - frontiersin.org
Background Understanding the biology of methicillin resistant Staphylococcus aureus
(MRSA) is crucial to unlocking insights for new targets in our fight against this antimicrobial …

Mutation in the two-component system regulator YycH leads to daptomycin tolerance in methicillin-resistant Staphylococcus aureus upon evolution with a population …

JE Sulaiman, L Wu, H Lam - Microbiology Spectrum, 2022 - journals.asm.org
Adaptive laboratory evolution (ALE) is a useful tool to study the evolution of antibiotic
tolerance in bacterial populations under diverse environmental conditions. The role of …

Proteome profiling of evolved methicillin-resistant Staphylococcus aureus strains with distinct daptomycin tolerance and resistance phenotypes

JE Sulaiman, L Long, PY Qian, H Lam - Frontiers in Microbiology, 2022 - frontiersin.org
Methicillin-resistant Staphylococcus aureus (MRSA) is a highly dangerous pathogen, and
daptomycin has been increasingly used to treat its infections in clinics. Recently, several …

Elasnin effectively eradicates daptomycin-resistant methicillin-resistant Staphylococcus aureus biofilms

JE Sulaiman, L Long, PY Qian, H Lam - Microbiology spectrum, 2022 - journals.asm.org
Elasnin is a recently reported antibiofilm agent that is effective against Gram-positive
bacteria including methicillin-resistant Staphylococcus aureus (MRSA). Remarkably, we …

多组学诠释食源性致病菌小菌落变种形成分子机制研究进展.

关鹏, 冻梓杰, 王淑莉, 姬生鑫… - Journal of Food …, 2023 - search.ebscohost.com
食源性致病菌在环境胁迫下可形成小菌落变种(small colony variants, SCVs),
被认为是其抗逆存活的重要调控方式之一. SCVs 的形成及防治给食品安全领域带来重大挑战 …

Proteomic Study of Antibiotic Tolerance and Resistance in Bacterial Populations From Adaptive Laboratory Evolution

JE Sulaiman - 2022 - search.proquest.com
It is known that bacterial populations could quickly adapt to antibiotic treatments by
becoming tolerant and resistant to the drug. Recently, adaptive laboratory evolution (ALE) …