IGF-binding proteins: why do they exist and why are there so many?

JB Allard, C Duan - Frontiers in endocrinology, 2018 - frontiersin.org
Insulin-like growth factors (IGFs) are key growth-promoting peptides that act as both
endocrine hormones and autocrine/paracrine growth factors. In the bloodstream and in local …

Evolution of gene duplication in plants

N Panchy, M Lehti-Shiu, SH Shiu - Plant physiology, 2016 - academic.oup.com
Ancient duplication events and a high rate of retention of extant pairs of duplicate genes
have contributed to an abundance of duplicate genes in plant genomes. These duplicates …

One thousand plant transcriptomes and the phylogenomics of green plants

Nature, 2019 - nature.com
Green plants (Viridiplantae) include around 450,000–500,000 species, of great diversity and
have important roles in terrestrial and aquatic ecosystems. Here, as part of the One …

Increased mutation and gene conversion within human segmental duplications

MR Vollger, PC Dishuck, WT Harvey, WS DeWitt… - Nature, 2023 - nature.com
Single-nucleotide variants (SNVs) in segmental duplications (SDs) have not been
systematically assessed because of the limitations of map** short-read sequencing data …

Gene duplication and evolution in recurring polyploidization–diploidization cycles in plants

X Qiao, Q Li, H Yin, K Qi, L Li, R Wang, S Zhang… - Genome biology, 2019 - Springer
Background The sharp increase of plant genome and transcriptome data provide valuable
resources to investigate evolutionary consequences of gene duplication in a range of taxa …

Genome evolution in the allotetraploid frog Xenopus laevis

AM Session, Y Uno, T Kwon, JA Chapman, A Toyoda… - Nature, 2016 - nature.com
To explore the origins and consequences of tetraploidy in the African clawed frog, we
sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis …

Pla2g12b drives expansion of triglyceride-rich lipoproteins

JH Thierer, O Foresti, PK Yadav, MH Wilson… - nature …, 2024 - nature.com
Vertebrates transport hydrophobic triglycerides through the circulatory system by packaging
them within amphipathic particles called Triglyceride-Rich Lipoproteins. Yet, it remains …

The Atlantic salmon genome provides insights into rediploidization

S Lien, BF Koop, SR Sandve, JR Miller, MP Kent… - Nature, 2016 - nature.com
The whole-genome duplication 80 million years ago of the common ancestor of salmonids
(salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique …

Evolution by gene loss

R Albalat, C Cañestro - Nature Reviews Genetics, 2016 - nature.com
The recent increase in genomic data is revealing an unexpected perspective of gene loss as
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …

The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization

K Du, M Stöck, S Kneitz, C Klopp… - Nature ecology & …, 2020 - nature.com
Sturgeons seem to be frozen in time. The archaic characteristics of this ancient fish lineage
place it in a key phylogenetic position at the base of the~ 30,000 modern teleost fish …