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IGF-binding proteins: why do they exist and why are there so many?
Insulin-like growth factors (IGFs) are key growth-promoting peptides that act as both
endocrine hormones and autocrine/paracrine growth factors. In the bloodstream and in local …
endocrine hormones and autocrine/paracrine growth factors. In the bloodstream and in local …
Evolution of gene duplication in plants
Ancient duplication events and a high rate of retention of extant pairs of duplicate genes
have contributed to an abundance of duplicate genes in plant genomes. These duplicates …
have contributed to an abundance of duplicate genes in plant genomes. These duplicates …
One thousand plant transcriptomes and the phylogenomics of green plants
Nature, 2019 - nature.com
Green plants (Viridiplantae) include around 450,000–500,000 species, of great diversity and
have important roles in terrestrial and aquatic ecosystems. Here, as part of the One …
have important roles in terrestrial and aquatic ecosystems. Here, as part of the One …
Increased mutation and gene conversion within human segmental duplications
Single-nucleotide variants (SNVs) in segmental duplications (SDs) have not been
systematically assessed because of the limitations of map** short-read sequencing data …
systematically assessed because of the limitations of map** short-read sequencing data …
Gene duplication and evolution in recurring polyploidization–diploidization cycles in plants
Background The sharp increase of plant genome and transcriptome data provide valuable
resources to investigate evolutionary consequences of gene duplication in a range of taxa …
resources to investigate evolutionary consequences of gene duplication in a range of taxa …
Genome evolution in the allotetraploid frog Xenopus laevis
To explore the origins and consequences of tetraploidy in the African clawed frog, we
sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis …
sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis …
Pla2g12b drives expansion of triglyceride-rich lipoproteins
Vertebrates transport hydrophobic triglycerides through the circulatory system by packaging
them within amphipathic particles called Triglyceride-Rich Lipoproteins. Yet, it remains …
them within amphipathic particles called Triglyceride-Rich Lipoproteins. Yet, it remains …
The Atlantic salmon genome provides insights into rediploidization
The whole-genome duplication 80 million years ago of the common ancestor of salmonids
(salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique …
(salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique …
Evolution by gene loss
The recent increase in genomic data is revealing an unexpected perspective of gene loss as
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …
The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization
Sturgeons seem to be frozen in time. The archaic characteristics of this ancient fish lineage
place it in a key phylogenetic position at the base of the~ 30,000 modern teleost fish …
place it in a key phylogenetic position at the base of the~ 30,000 modern teleost fish …