Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of …
Background Among patients who had an ischaemic stroke presenting directly to a stroke
centre where endovascular thrombectomy (EVT) is immediately available, there is …
centre where endovascular thrombectomy (EVT) is immediately available, there is …
Advances in the management of acute ischemic stroke
R Nair, AN Wagner, BH Buck - Current Opinion in Neurology, 2023 - journals.lww.com
Converging evidence has demonstrated that for patients with ischemic stroke presenting at
under 4.5 h from the onset, TNK is comparable to alteplase. These data along with the …
under 4.5 h from the onset, TNK is comparable to alteplase. These data along with the …
Tenecteplase improves reperfusion across time in large vessel stroke
Objective Tenecteplase improves reperfusion compared to alteplase in patients with large
vessel occlusions. To determine whether this improvement varies across the spectrum of …
vessel occlusions. To determine whether this improvement varies across the spectrum of …
Outcomes after endovascular thrombectomy with or without alteplase in routine clinical practice
Importance The effectiveness and safety of intravenous alteplase given before or
concurrently with endovascular thrombectomy (EVT) is uncertain. Randomized clinical trials …
concurrently with endovascular thrombectomy (EVT) is uncertain. Randomized clinical trials …
Tenecteplase treatment and thrombus characteristics associated with early reperfusion: an EXTEND-IA TNK trials analysis
Background: Intracranial occlusion site, contrast permeability, and clot burden are thrombus
characteristics that influence alteplase-associated reperfusion. In this study, we assessed …
characteristics that influence alteplase-associated reperfusion. In this study, we assessed …
Strength of association between infarct volume and clinical outcome depends on the magnitude of infarct size: results from the ESCAPE-NA1 trial
BACKGROUND AND PURPOSE: Infarct volume is an important predictor of clinical outcome
in acute stroke. We hypothesized that the association of infarct volume and clinical outcome …
in acute stroke. We hypothesized that the association of infarct volume and clinical outcome …
Association of intravenous alteplase, early reperfusion, and clinical outcome in patients with large vessel occlusion stroke: post hoc analysis of the randomized …
Background: The added value of intravenous alteplase in reperfusing ischemic brain tissue
in patients undergoing endovascular treatment and directly presented to an endovascular …
in patients undergoing endovascular treatment and directly presented to an endovascular …
Tenecteplase versus alteplase before mechanical thrombectomy: experience from a US healthcare system undergoing a system-wide transition of primary …
Background Tenecteplase (TNK) is a genetically modified variant of alteplase (TPA) and has
been established as a non-inferior alternative to TPA in acute ischemic stroke (AIS). Whether …
been established as a non-inferior alternative to TPA in acute ischemic stroke (AIS). Whether …
Early recanalization in large-vessel occlusion stroke patients transferred for endovascular treatment
NA Terreros, AAE Bruggeman… - Journal of …, 2022 - jnis.bmj.com
Background We performed an exploratory analysis to identify patient and thrombus
characteristics associated with early recanalization in large-vessel occlusion (LVO) stroke …
characteristics associated with early recanalization in large-vessel occlusion (LVO) stroke …
Endovascular thrombectomy and intravenous alteplase in patients with acute ischemic stroke due to large vessel occlusion: a clinical practice guideline
Aim Whether or not use of intravenous alteplase in combination with endovascular
thrombectomy (EVT) improves outcomes versus EVT alone, for acute stroke patients with …
thrombectomy (EVT) improves outcomes versus EVT alone, for acute stroke patients with …