During division, eukaryotic cells undergo a dramatic, complex and coordinated remodelling
of their cytoskeleton and membranes. For cell division to occur, chromosomes must be …

Cytokinesis mediates the physical separation of dividing cells after chromosome
segregation. In animal cell cytokinesis, a contractile ring, mainly composed of actin and …

The active form of the small GTPase RhoA is necessary and sufficient for formation of a
cytokinetic furrow in animal cells. Despite the conceptual simplicity of the process, the …

The conserved polarity effector proteins PAR-3, PAR-6, CDC-42, and atypical protein kinase
C (aPKC) form a core unit of the PAR protein network, which plays a central role in …

Cell division ends with the physical separation of the two daughter cells, a process known as
cytokinesis. This final event ensures that nuclear and cytoplasmic contents are accurately …

Cytokinesis is the process of physical cleavage at the end of cell division; it proceeds by
ingression of an acto-myosin furrow at the equator of the cell. Its failure leads to …

Crosstalk between the actin cytoskeleton and microtubules promotes symmetry break to
polarize cells for division, shape changes, and migration. These cellular events are crucial …

Every cell becomes two through a carefully orchestrated process of division. Prior to division,
contractile machinery must first be assembled at the cell midzone to ensure that the cut …

Here, we will review the evidence showing that mitotic exit is initiated by regulated
proteolysis and then driven by the PPP family of phosphoserine/threonine phosphatases …

Division of amoebas, fungi, and animal cells into two daughter cells at the end of the cell
cycle depends on a common set of ancient proteins, principally actin filaments and myosin-II …