In vitro and in vivo studies of Syzygium cumini-loaded electrospun PLGA/PMMA/collagen nanofibers for accelerating topical wound healing
This work aims to develop plant extract-loaded electrospun nanofiber as an effective wound
dressing scaffolds for topical wound healing. Electrospun nanofibers were fabricated from …
dressing scaffolds for topical wound healing. Electrospun nanofibers were fabricated from …
Development of carvedilol-loaded albumin-based nanoparticles with factorial design to optimize in vitro and in vivo performance
Carvedilol, an anti-hypertensive medication commonly prescribed by healthcare providers,
falls under the BCS class II category due to its low-solubility and high-permeability …
falls under the BCS class II category due to its low-solubility and high-permeability …
Burst Release from In Situ Forming PLGA-Based Implants: 12 Effectors and Ways of Correction
EO Bakhrushina, PS Sakharova, PD Konogorova… - Pharmaceutics, 2024 - mdpi.com
In modern pharmaceutical technology, modified-release dosage forms, such as in situ
formed implants, are gaining rapidly in popularity. These dosage forms are created based …
formed implants, are gaining rapidly in popularity. These dosage forms are created based …
Atorvastatin loaded lecithin-coated zein nanoparticles based thermogel for the intra-articular management of osteoarthritis: in-silico, in-vitro, and in-vivo studies
Purpose Up-to-date literature offers limited data about utilizing atorvastatin calcium (ATV) as
a promising chondroprotective agent in osteoarthritis (OA). So, this study aims to develop a …
a promising chondroprotective agent in osteoarthritis (OA). So, this study aims to develop a …
[HTML][HTML] Fabrication and Optimization of a Silodosin In Situ-Forming PLGA Implants for the Treatment of Benign Prostatic Hyperplasia: In Vitro and In Vivo Study
Objectives: Lower urinary tract symptoms (LUTSs) related to benign prostatic hyperplasia
(BPH) are common in older men, and alpha-adrenoceptor blockers continue to be a key part …
(BPH) are common in older men, and alpha-adrenoceptor blockers continue to be a key part …
Formulation and optimization of olanzapine-carboxylic acid cocrystals orodispersible tablets: In-vitro/In-vivo study
Oromucosal delivery of olanzapine (OLZ) is an optimal strategy to overcome low oral
bioavailability as well as improve medication adherence. However, its poor aqueous …
bioavailability as well as improve medication adherence. However, its poor aqueous …
Polymeric linagliptin nanoparticles as a sustained release treatment for type 2 diabetes
Linagliptin (Lina) is a DPP-4 inhibitor used to treat type II diabetes. However, it has a poor
oral bioavailability of 29.5% due to both first-pass effect and P-glycoprotein efflux, offering a …
oral bioavailability of 29.5% due to both first-pass effect and P-glycoprotein efflux, offering a …
Phase Inversion-Based Doxycycline Hyclate-Incorporated Borneol In Situ Gel for Periodontitis Treatment
N Lertsuphotvanit, S Tuntarawongsa, T Chantadee… - Gels, 2023 - mdpi.com
Borneol has been successfully employed as a gelling agent for in situ forming gel (ISG).
While 40% borneol can regulate drug release, there is interest in novel approaches to …
While 40% borneol can regulate drug release, there is interest in novel approaches to …