A comprehensive review of m6A/m6Am RNA methyltransferase structures
S Oerum, V Meynier, M Catala, C Tisné - Nucleic acids research, 2021 - academic.oup.com
Gene expression is regulated at many levels including co-or post-transcriptionally, where
chemical modifications are added to RNA on riboses and bases. Expression control via RNA …
chemical modifications are added to RNA on riboses and bases. Expression control via RNA …
Insights into N6-methyladenosine and programmed cell death in cancer
L Liu, H Li, D Hu, Y Wang, W Shao, J Zhong, S Yang… - Molecular cancer, 2022 - Springer
Abstract N6-methyladenosine (m6A) methylation, the most common form of internal RNA
modification in eukaryotes, has gained increasing attention and become a hot research topic …
modification in eukaryotes, has gained increasing attention and become a hot research topic …
The roles of DNA, RNA and histone methylation in ageing and cancer
Chromatin is a macromolecular complex predominantly comprising DNA, histone proteins
and RNA. The methylation of chromatin components is highly conserved as it helps …
and RNA. The methylation of chromatin components is highly conserved as it helps …
The roles of microRNAs in epigenetic regulation
MicroRNAs (miRNAs) are small noncoding RNAs, approximately 18–25 nucleotides in
length, now recognized as one of the major regulatory gene families in eukaryotes. Recent …
length, now recognized as one of the major regulatory gene families in eukaryotes. Recent …
Interaction between N6-methyladenosine (m6A) modification and noncoding RNAs in cancer
Y Chen, Y Lin, Y Shu, J He, W Gao - Molecular cancer, 2020 - Springer
As a critical internal RNA modification in higher eukaryotes, N 6-methyladenosine (m 6 A)
has become the hotspot of epigenetics research in recent years. Extensive studies on …
has become the hotspot of epigenetics research in recent years. Extensive studies on …
The FTO/miR‐181b‐3p/ARL5B signaling pathway regulates cell migration and invasion in breast cancer
Y Xu, S Ye, N Zhang, S Zheng, H Liu… - Cancer …, 2020 - Wiley Online Library
Abstract Background N6‐methyladenosine (m6A) RNA modification has been demonstrated
to be a significant regulatory process in the progression of various tumors, including breast …
to be a significant regulatory process in the progression of various tumors, including breast …
Small RNA modifications: regulatory molecules and potential applications
Q **ong, Y Zhang - Journal of Hematology & Oncology, 2023 - Springer
Small RNAs (also referred to as small noncoding RNAs, sncRNA) are defined as polymeric
ribonucleic acid molecules that are less than 200 nucleotides in length and serve a variety of …
ribonucleic acid molecules that are less than 200 nucleotides in length and serve a variety of …
RNA methyltransferase METTL16: Targets and function
Abstract The N6‐methyladenosine (m6A) RNA methyltransferase METTL16 is an emerging
player in the RNA modification landscape of the human cell. Originally thought to be a …
player in the RNA modification landscape of the human cell. Originally thought to be a …
RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation
Y Yue, J Liu, C He - Genes & development, 2015 - genesdev.cshlp.org
N 6-methyladenosine (m6A) is the most prevalent and internal modification that occurs in the
messenger RNAs (mRNA) of most eukaryotes, although its functional relevance remained a …
messenger RNAs (mRNA) of most eukaryotes, although its functional relevance remained a …
[HTML][HTML] Critical roles of FTO-mediated mRNA m6A demethylation in regulating adipogenesis and lipid metabolism: Implications in lipid metabolic disorders
Z Yang, G Yu, X Zhu, T Peng, Y Lv - Genes & diseases, 2022 - Elsevier
The goal this review is to clarify the effects of the fat mass and obesity-associated protein
(FTO) in lipid metabolism regulation and related underlying mechanisms through the FTO …
(FTO) in lipid metabolism regulation and related underlying mechanisms through the FTO …