Validation of biomarkers of aging
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
Challenges and recommendations for the translation of biomarkers of aging
Biomarkers of Aging Consortium, CMS Herzog… - Nature Aging, 2024 - nature.com
Biomarkers of aging (BOA) are quantitative parameters that predict biological age and
ideally its changes in response to interventions. In recent years, many promising molecular …
ideally its changes in response to interventions. In recent years, many promising molecular …
PRC2-AgeIndex as a universal biomarker of aging and rejuvenation
DNA methylation (DNAm) is one of the most reliable biomarkers of aging across mammalian
tissues. While the age-dependent global loss of DNAm has been well characterized, DNAm …
tissues. While the age-dependent global loss of DNAm has been well characterized, DNAm …
Causality-enriched epigenetic age uncouples damage and adaptation
Abstract Machine learning models based on DNA methylation data can predict biological
age but often lack causal insights. By harnessing large-scale genetic data through …
age but often lack causal insights. By harnessing large-scale genetic data through …
[HTML][HTML] Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity
The recent unprecedented progress in ageing research and drug discovery brings together
fundamental research and clinical applications to advance the goal of promoting healthy …
fundamental research and clinical applications to advance the goal of promoting healthy …
pyaging: a Python-based compendium of GPU-optimized aging clocks
LP de Lima Camillo - Bioinformatics, 2024 - academic.oup.com
Motivation Aging is intricately linked to diseases and mortality. It is reflected in molecular
changes across various tissues which can be leveraged for the development of biomarkers …
changes across various tissues which can be leveraged for the development of biomarkers …
Causal inference for epigenetic ageing
K Ying - Nature Reviews Genetics, 2024 - nature.com
Causal inference for epigenetic ageing | Nature Reviews Genetics Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …
you for visiting nature.com. You are using a browser version with limited support for CSS. To …
[HTML][HTML] Epigenetic Biomarkers Driven by Environmental Toxins Associated with Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis in the …
ME Newell, A Aravindan, A Babbrah, RU Halden - Toxics, 2025 - mdpi.com
Environmental toxins and epigenetic changes have been linked to neurodegenerative
diseases, including Alzheimer's Disease (AD), Parkinson's Disease (PD), and amyotrophic …
diseases, including Alzheimer's Disease (AD), Parkinson's Disease (PD), and amyotrophic …
estiMAge: development of a DNA methylation clock to estimate the methylation age of single cells
Z Saßmannshausen, L Blank… - Bioinformatics …, 2025 - academic.oup.com
Motivation Since their introduction about 10 years ago, methylation clocks have provided
broad insights into the biological age of different species, tissues, and in the context of …
broad insights into the biological age of different species, tissues, and in the context of …
[PDF][PDF] Poganik
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …