The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …

Biomarkers of aging (BOA) are quantitative parameters that predict biological age and
ideally its changes in response to interventions. In recent years, many promising molecular …

DNA methylation (DNAm) is one of the most reliable biomarkers of aging across mammalian
tissues. While the age-dependent global loss of DNAm has been well characterized, DNAm …

Abstract Machine learning models based on DNA methylation data can predict biological
age but often lack causal insights. By harnessing large-scale genetic data through …

The recent unprecedented progress in ageing research and drug discovery brings together
fundamental research and clinical applications to advance the goal of promoting healthy …

Motivation Aging is intricately linked to diseases and mortality. It is reflected in molecular
changes across various tissues which can be leveraged for the development of biomarkers …

Causal inference for epigenetic ageing | Nature Reviews Genetics Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Environmental toxins and epigenetic changes have been linked to neurodegenerative
diseases, including Alzheimer's Disease (AD), Parkinson's Disease (PD), and amyotrophic …

Motivation Since their introduction about 10 years ago, methylation clocks have provided
broad insights into the biological age of different species, tissues, and in the context of …

The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …