Bromelain, a Group of Pineapple Proteolytic Complex Enzymes (Ananas comosus) and Their Possible Therapeutic and Clinical Effects. A Summary

C Varilla, M Marcone, L Paiva, J Baptista - Foods, 2021 - mdpi.com
Bromelain is a complex combination of multiple endopeptidases of thiol and other
compounds derived from the pineapple fruit, stem and/or root. Fruit bromelain and stem …

Bromelain: an overview of industrial application and purification strategies

ZIM Arshad, A Amid, F Yusof, I Jaswir, K Ahmad… - Applied microbiology …, 2014 - Springer
This review highlights the use of bromelain in various applications with up-to-date literature
on the purification of bromelain from pineapple fruit and waste such as peel, core, crown …

Semiconducting polymer nanoenzymes with photothermic activity for enhanced cancer therapy

J Li, C **e, J Huang, Y Jiang, Q Miao… - Angewandte Chemie …, 2018 - Wiley Online Library
Regulation of enzyme activity is fundamentally challenging but practically meaningful for
biology and medicine. However, noninvasive remote control of enzyme activity in living …

Pineapple peel waste valorization for extraction of bio-active compounds and protein: Microwave assisted method and Box Behnken design optimization

SP Bansod, JK Parikh, PK Sarangi - Environmental Research, 2023 - Elsevier
Pineapple peel waste (PPW) is obtained in huge quantities out of pineapple canning
industries and it is found to be rich in bioactive compounds with antioxidant activity and an …

An integrated approach for pineapple waste valorisation. Bioethanol production and bromelain extraction from pineapple residues

LS Gil, PF Maupoey - Journal of Cleaner Production, 2018 - Elsevier
Waste management is critical for the food industry for which there is increasing interest in
food waste valorisation processes. Pineapple waste, an abundant agro-industrial residue, is …

Production of plant proteases and new biotechnological applications: an updated review

F David Troncoso, D Alberto Sánchez… - …, 2022 - Wiley Online Library
An updated review of emerging plant proteases with potential biotechnological application is
presented. Plant proteases show comparable or even greater performance than animal or …

Plant protease inhibitors in therapeutics-focus on cancer therapy

S Srikanth, Z Chen - Frontiers in pharmacology, 2016 - frontiersin.org
Plants are known to have many secondary metabolites and phytochemical compounds
which are highly explored at biochemical and molecular genetics level and exploited …

Anticancer properties of bromelain: State-of-the-art and recent trends

R Pezzani, M Jimenez-Garcia, X Capo… - Frontiers in …, 2023 - frontiersin.org
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …

Bromelain and nisin: The natural antimicrobials with high potential in biomedicine

U Jančič, S Gorgieva - Pharmaceutics, 2021 - mdpi.com
Infectious diseases along with various cancer types are among the most significant public
health problems and the leading cause of death worldwide. The situation has become even …

Stability, purification, and applications of bromelain: A review

LC de Lencastre Novaes, AF Jozala… - Biotechnology …, 2016 - Wiley Online Library
Bromelain is a cysteine protease found in pineapple tissue. Because of its anti‐inflammatory
and anti‐cancer activities, as well as its ability to induce apoptotic cell death, bromelain has …