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The drug repurposing for COVID-19 clinical trials provide very effective therapeutic combinations: lessons learned from major clinical studies
SARS-CoV-2 has spread across the globe in no time. In the beginning, people suffered due
to the absence of efficacious drugs required to treat severely ill patients. Nevertheless, still …
to the absence of efficacious drugs required to treat severely ill patients. Nevertheless, still …
Drug repurposing using real-world data
Highlights•250 records, including 144 original studies, met the eligibility criteria for inclusion
in this review.•Studies evaluated repurposing mainly for cardiovascular disease, COVID-19 …
in this review.•Studies evaluated repurposing mainly for cardiovascular disease, COVID-19 …
Effectiveness of Drug repurposing and natural products against SARS-CoV-2: a comprehensive review
Abstract The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a
betacoronavirus responsible for the COVID-19 pandemic, causing respiratory disorders, and …
betacoronavirus responsible for the COVID-19 pandemic, causing respiratory disorders, and …
New drug discovery
B Yingngam - Multidisciplinary Applications of Natural Science for …, 2023 - igi-global.com
The field of drug discovery is continually advancing with the emergence of new technologies
and scientific developments. Moreover, there is a recent growing interest in exploiting …
and scientific developments. Moreover, there is a recent growing interest in exploiting …
Structure-based drug design of RdRp inhibitors against SARS-CoV-2
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
worldwide pandemic since 2019, spreading rapidly and posing a significant threat to human …
worldwide pandemic since 2019, spreading rapidly and posing a significant threat to human …
Pharmacoinformatics-based phytochemical screening for anticancer impacts of yellow sweet clover, Melilotus officinalis (Linn.) Pall
To date, much attention has been paid to phytochemicals because of their diverse
pharmacological effects on a variety of diseases such as cancer. In this regard, computer …
pharmacological effects on a variety of diseases such as cancer. In this regard, computer …
Drug repurposing against SARS-CoV-2 using computational approaches
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
generated a critical need for treatments to reduce morbidity and mortality associated with …
generated a critical need for treatments to reduce morbidity and mortality associated with …
Plant-Derived Natural Non-Nucleoside Analog Inhibitors (NNAIs) against RNA-Dependent RNA Polymerase Complex (nsp7/nsp8/nsp12) of SARS-CoV-2
The emergence of fast-spreading SARS-CoV-2 mutants has sparked a new phase of COVID-
19 pandemic. There is a dire necessity for antivirals targeting highly conserved genomic …
19 pandemic. There is a dire necessity for antivirals targeting highly conserved genomic …
A comprehensive update on CIDO: the community-based coronavirus infectious disease ontology
Background The current COVID-19 pandemic and the previous SARS/MERS outbreaks of
2003 and 2012 have resulted in a series of major global public health crises. We argue that …
2003 and 2012 have resulted in a series of major global public health crises. We argue that …
MEDIATE-Molecular DockIng at homE: Turning collaborative simulations into therapeutic solutions
Introduction Collaborative computing has attracted great interest, enabling researchers
worldwide to come together and work seamlessly. Its relevance has never been so apparent …
worldwide to come together and work seamlessly. Its relevance has never been so apparent …