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The Caenorhabditis elegans Transgenic Toolbox
J Nance, C Frøkjær-Jensen - Genetics, 2019 - academic.oup.com
The power of any genetic model organism is derived, in part, from the ease with which gene
expression can be manipulated. The short generation time and invariant developmental …
expression can be manipulated. The short generation time and invariant developmental …
The biogenesis and biological function of PIWI-interacting RNA in cancer
S Chen, S Ben, J **n, S Li, R Zheng, H Wang… - Journal of hematology & …, 2021 - Springer
Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …
piRBase: a comprehensive database of piRNA sequences
J Wang, P Zhang, Y Lu, Y Li, Y Zheng… - Nucleic acids …, 2019 - academic.oup.com
PIWI-interacting RNAs are a class of small RNAs that is most abundantly expressed in
animal germline. Substantial research is going on to reveal the functions of piRNAs in the …
animal germline. Substantial research is going on to reveal the functions of piRNAs in the …
Engineering rules that minimize germline silencing of transgenes in simple extrachromosomal arrays in C. elegans
Transgenes are prone to progressive silencing due to their structure, copy number, and
genomic location. In C. elegans, repressive mechanisms are particularly strong in the …
genomic location. In C. elegans, repressive mechanisms are particularly strong in the …
A tudor domain protein, SIMR-1, promotes siRNA production at piRNA-targeted mRNAs in C. elegans
piRNAs play a critical role in the regulation of transposons and other germline genes. In
Caenorhabditis elegans, regulation of piRNA target genes is mediated by the mutator …
Caenorhabditis elegans, regulation of piRNA target genes is mediated by the mutator …
A review of discovery profiling of PIWI-interacting RNAs and their diverse functions in metazoans
S Huang, K Yoshitake, S Asakawa - International Journal of Molecular …, 2021 - mdpi.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs (sncRNAs) that
perform crucial biological functions in metazoans and defend against transposable elements …
perform crucial biological functions in metazoans and defend against transposable elements …
piR-823 tale as emerging cancer-hallmark molecular marker in different cancer types: a step-toward ncRNA-precision
PIWI-interacting RNAs (piRNAs) have received a lot of attention for their functions in cancer
research. This class of short non-coding RNAs (ncRNA) has roles in genomic stability …
research. This class of short non-coding RNAs (ncRNA) has roles in genomic stability …
Split-wrmScarlet and split-sfGFP: tools for faster, easier fluorescent labeling of endogenous proteins in Caenorhabditis elegans
J Goudeau, CS Sharp, J Paw, L Savy, MD Leonetti… - Genetics, 2021 - academic.oup.com
We create and share a new red fluorophore, along with a set of strains, reagents and
protocols, to make it faster and easier to label endogenous Caenorhabditis elegans proteins …
protocols, to make it faster and easier to label endogenous Caenorhabditis elegans proteins …
[HTML][HTML] Identification of piRNA disease associations using deep learning
Piwi-interacting RNAs (piRNAs) play a pivotal role in maintaining genome integrity by
repression of transposable elements, gene stability, and association with various disease …
repression of transposable elements, gene stability, and association with various disease …
piRTarBase: a database of piRNA targeting sites and their roles in gene regulation
PIWI-interacting RNAs (piRNAs) are a class of small noncoding RNAs that guard animal
genomes against mutation by silencing transposons. In addition, recent studies have …
genomes against mutation by silencing transposons. In addition, recent studies have …