The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Flowing blood generates a frictional force called shear stress that has major effects on
vascular function. Branches and bends of arteries are exposed to complex blood flow …

Atherosclerosis, the chronic accumulation of cholesterol-rich plaque within arteries, is
associated with a broad spectrum of cardiovascular diseases including myocardial …

Atherosclerotic diseases such as myocardial infarction, ischaemic stroke and peripheral
artery disease continue to be leading causes of death worldwide despite the success of …

Background: The transcription factor BACH1 (BTB and CNC homology 1) suppressed
endothelial cells (ECs) proliferation and migration and impaired angiogenesis in the …

Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …

Pulmonary atelectasis is common in the perioperative period. Physiologically, it is produced
when collapsing forces derived from positive pleural pressure and surface tension overcome …

Complex multicellular life in mammals relies on functional cooperation of different organs for
the survival of the whole organism. The kidneys play a critical part in this process through …