Metagenomic analysis using phylogenetic placement—a review of the first decade
Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and
interpret the tsunami of metagenomic sequencing data generated by high-throughput …
interpret the tsunami of metagenomic sequencing data generated by high-throughput …
Expanding functional protein sequence spaces using generative adversarial networks
D Repecka, V Jauniskis, L Karpus… - Nature Machine …, 2021 - nature.com
De novo protein design for catalysis of any desired chemical reaction is a long-standing goal
in protein engineering because of the broad spectrum of technological, scientific and …
in protein engineering because of the broad spectrum of technological, scientific and …
Genesis and Gappa: processing, analyzing and visualizing phylogenetic (placement) data
We present genesis, a library for working with phylogenetic data, and gappa, an
accompanying command-line tool for conducting typical analyses on such data. The tools …
accompanying command-line tool for conducting typical analyses on such data. The tools …
The last common ancestor of most bilaterian animals possessed at least nine opsins
The opsin gene family encodes key proteins animals use to sense light and has expanded
dramatically as it originated early in animal evolution. Understanding the origins of opsin …
dramatically as it originated early in animal evolution. Understanding the origins of opsin …
Reclassification of family A DNA polymerases reveals novel functional subfamilies and distinctive structural features
Abstract Family A DNA polymerases (PolAs) form an important and well-studied class of
extant polymerases participating in DNA replication and repair. Nonetheless, despite the …
extant polymerases participating in DNA replication and repair. Nonetheless, despite the …
Study of the error correction capability of multiple sequence alignment algorithm (MAFFT) in DNA storage
R ** by 17 aligners on simulated and empirical NGS data: an updated comparison of DNA-and RNA-Seq data from Illumina and …
L Donato, C Scimone, C Rinaldi, R D'Angelo… - Neural Computing and …, 2021 - Springer
Abstract During the last (15) years, improved omics sequencing technologies have
expanded the scale and resolution of various biological applications, generating high …
expanded the scale and resolution of various biological applications, generating high …
Computational approaches to study the effects of small genomic variations
K Khafizov, MV Ivanov, OV Glazova… - Journal of molecular …, 2015 - Springer
Advances in DNA sequencing technologies have led to an avalanche-like increase in the
number of gene sequences deposited in public databases over the last decade as well as …
number of gene sequences deposited in public databases over the last decade as well as …